ID   CCNB2_MEDSA             Reviewed;         328 AA.
AC   P30278;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=G2/mitotic-specific cyclin-2;
DE   AltName: Full=B-like cyclin;
DE   AltName: Full=CycMs2;
DE   Flags: Fragment;
OS   Medicago sativa (Alfalfa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1307238; DOI=10.2307/3869496;
RA   Hirt H., Mink M., Pfosser M., Boegre L., Gyoergyey J., Jonak C.,
RA   Gartner A., Dudits D., Heberle-Bors E.;
RT   "Alfalfa cyclins: differential expression during the cell cycle and in
RT   plant organs.";
RL   Plant Cell 4:1531-1538(1992).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition.
CC   -!- SUBUNIT: Interacts with the CDC2 protein kinase to form a
CC       serine/threonine kinase holoenzyme complex also known as maturation
CC       promoting factor (MPF). The cyclin subunit imparts substrate
CC       specificity to the complex.
CC   -!- TISSUE SPECIFICITY: Only expressed in organs with dividing cells.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X68741; CAA48675.1; -; mRNA.
DR   PIR; PQ0490; S29925.
DR   AlphaFoldDB; P30278; -.
DR   SMR; P30278; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           <1..328
FT                   /note="G2/mitotic-specific cyclin-2"
FT                   /id="PRO_0000080393"
FT   NON_TER         1
SQ   SEQUENCE   328 AA;  37711 MW;  7E4CCB166B5D949E CRC64;
     NSNEFGNFIA IDDELKLPED QPEPMTLEHT EPMHSDPLEM EEVEMEDIEG EMILDIDSCD
     ANNSLAVVEY IEDLHAYYRK IEYLGCVSPT YMDEQLDLNE RMRAILVDWL IEVHDKFDLM
     QETLFLTVNL IDRFLAKQNV VRKKLQLVGL VAMLLACKYE EVSVPVVSDL IHIADRAYTR
     KDILEMEKLM LNTLQYNMSL PTAYVFMRRF LKAAQADKKL ELVAFFLVDL SLVEYEMLKF
     PPSLVAAAAV YTAQCTVSGF KHWNKTCEWH TNYSEDQLLE CSMLMVGFHQ KAGAGKLTGV
     HRKYGSAKFS FTAKCEPACF LLENKNQP