ID   CCNB2_ORYJA             Reviewed;         382 AA.
AC   Q9DG99;
DT   27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=G2/mitotic-specific cyclin-B2;
GN   Name=ccnb2;
OS   Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=123683;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Ovary;
RA   Yamashita M., Mita K.;
RT   "cDNA cloning of Cdc2 and cyclin B in medaka species.";
RL   Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the CDK1 protein kinase to form a
CC       serine/threonine kinase holoenzyme complex also known as maturation
CC       promoting factor (MPF). The cyclin subunit imparts substrate
CC       specificity to the complex (By similarity). {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AB050464; BAB17222.1; -; mRNA.
DR   AlphaFoldDB; Q9DG99; -.
DR   SMR; Q9DG99; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           1..382
FT                   /note="G2/mitotic-specific cyclin-B2"
FT                   /id="PRO_0000080367"
FT   REGION          1..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   382 AA;  42995 MW;  992F7F0EE2816366 CRC64;
     MSSVEAVTQQ QLLAAENPVR MGKGAADPRR AALGEITNRN AAAAANRKMG PSKKQPKPSC
     AQKPQPVVHT SAGDPAPISA DMSMKVEQDL SQAFSEVLML AVQDVDEQDA DQPQLCSQYV
     KDIYKYLHTL EEQQAIRPNY MQGYSVTEHM RALLVDWLVQ VHSRFQLLQE TLYLTVAILD
     RFLQVHPVSR RKLQLVGVTA MLVACKYEEM YPPEVGDFAY ITDDAFTKFQ IVEMEQVILR
     SLGFQLGRPL PLHFLRRASK VADADVEKHT LAKYLLELTL LDYHMVHYRP SEAAAAALCL
     SQLLLDGLPW SLEQQHYSTY DEQHLKPIMQ LMAKNVVQVT EGRTKFLAVK KKYSSSKLMK
     ISLIPQLNSS TIKVMAEALQ NP