ID   CCNB2_RANJA             Reviewed;         392 AA.
AC   O93229;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=G2/mitotic-specific cyclin-B2;
GN   Name=CCNB2;
OS   Rana japonica (Japanese reddish frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana.
OX   NCBI_TaxID=8402;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Ovary;
RX   PubMed=9669534;
RX   DOI=10.1002/(sici)1098-2795(199808)50:4<499::aid-mrd14>3.0.co;2-y;
RA   Ihara J., Yoshida N., Tanaka T., Mita K., Yamashita M.;
RT   "Either cyclin B1 or B2 is necessary and sufficient for inducing germinal
RT   vesicle breakdown during frog (Rana japonica) oocyte maturation.";
RL   Mol. Reprod. Dev. 50:499-509(1998).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition.
CC   -!- SUBUNIT: Interacts with the CDK1 protein kinase to form a
CC       serine/threonine kinase holoenzyme complex also known as maturation
CC       promoting factor (MPF). The cyclin subunit imparts substrate
CC       specificity to the complex.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB005253; BAA32563.1; -; mRNA.
DR   AlphaFoldDB; O93229; -.
DR   SMR; O93229; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           1..392
FT                   /note="G2/mitotic-specific cyclin-B2"
FT                   /id="PRO_0000080370"
SQ   SEQUENCE   392 AA;  43961 MW;  5038C4F8351CC9C8 CRC64;
     MATRRAAIAR EVDNAVGAMR SKAQLNGRRA ALGEIGNKVT VRAVKQPAKN SNTTSKTTRP
     VAKVSNVSVK PKAVTVTEAP SQVKEASPVP MDVSMKEEEE LCQAFSEVLN HVVDIDAEDG
     GNPQLCSEYV VDIYNYLRER EVQQSIKQRY LDGMEINERM RAILVDWLIQ VNSRFQFLQE
     TLYMGIAIMD RFLQVQPISR GKLQLVGVTS LLLASKYEEM YSPEVADFAY ITDNAYTTSQ
     IREMEMIILR ELKFDLGRPL PLHFLRRASK ACSADAEQHT LAKYLMELTL VDYEMVHFHP
     SEIAAAALCL AQKVLGVGSW GSTQHHYTGY TEEDLTPIIK HIAKNVTKVN QNRTKHVAVR
     NKYASSKLMK ISTHPQLMSL VITELAASLT SQ