CCNB_HYDVU
ID CCNB_HYDVU Reviewed; 361 AA.
AC P51988;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=G2/mitotic-specific cyclin-B;
DE Flags: Fragment;
OS Hydra vulgaris (Hydra) (Hydra attenuata).
OC Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC Aplanulata; Hydridae; Hydra.
OX NCBI_TaxID=6087;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8743953; DOI=10.1242/jcs.109.5.1063;
RA Scheurlen-Blchle I., Hoffmeister S., Herrmans-Borgmeyer I., Schaller H.C.;
RT "Presence and expression of G2 cyclins in the coelenterate hydra.";
RL J. Cell Sci. 109:1063-1069(1996).
CC -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC (mitosis) transition. Interacts with the CDC2 protein kinase to form
CC MPF. G2/M cyclins accumulate steadily during G2 and are abruptly
CC destroyed at mitosis (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
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DR EMBL; X90985; CAA62472.1; -; mRNA.
DR AlphaFoldDB; P51988; -.
DR SMR; P51988; -.
DR Proteomes; UP000694840; Unplaced.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177; PTHR10177; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Cyclin; Mitosis; Reference proteome.
FT CHAIN <1..361
FT /note="G2/mitotic-specific cyclin-B"
FT /id="PRO_0000080383"
FT NON_TER 1
SQ SEQUENCE 361 AA; 41400 MW; F5A0ECF78C6E0CAB CRC64;
SSRTVLSNIS NIQRRPQVVG KIKKEDGVAL EEKAPLNKGL GRMVSQSNLI SDVQLKTTKI
IPAYQDIADV EVPINAMINS FTELEVDDID LEDLGNPTLC AEYLKDIYKY MNKLERRLEP
SDYMAHQAEI NFKMRSILVD WLIQVQSRFN LLQETLYLTI YIIDRYLSKQ NVKRAELQLE
GVTAMLIASK YEEMYAPEIG DFVYITDNAY SKEKIRQMEQ KMLKTCEYDF SNPLCLHFLR
RNSKAGAVDA QKHTLAKYLM ELTLVEYEFI TKLPSEIAAA ALYLALKLID DSNWTPTLAH
YSGYTEDEIL STVSKLSILT LSMDNSKYQA VKNKYSASKF LRISLIPQLK GHILSKFAER
N