ID   CCNB_SPISO              Reviewed;         428 AA.
AC   P13952;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=G2/mitotic-specific cyclin-B;
OS   Spisula solidissima (Atlantic surf-clam).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Heteroconchia; Euheterodonta; Imparidentia; Neoheterodontei;
OC   Venerida; Mactroidea; Mactridae; Spisula.
OX   NCBI_TaxID=6584;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2522454; DOI=10.1083/jcb.108.4.1431;
RA   Westendorf J.M., Swenson K.I., Ruderman J.V.;
RT   "The role of cyclin B in meiosis I.";
RL   J. Cell Biol. 108:1431-1444(1989).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G2/M
CC       (mitosis) transition.
CC   -!- SUBUNIT: Interacts with the CDC2 protein kinase to form a
CC       serine/threonine kinase holoenzyme complex also known as maturation
CC       promoting factor (MPF). The cyclin subunit imparts substrate
CC       specificity to the complex.
CC   -!- DEVELOPMENTAL STAGE: Accumulates steadily during G2 and is abruptly
CC       destroyed at mitosis.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC       {ECO:0000305}.
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DR   EMBL; X15485; CAA33513.1; -; mRNA.
DR   PIR; A30108; A30108.
DR   AlphaFoldDB; P13952; -.
DR   SMR; P13952; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis.
FT   CHAIN           1..428
FT                   /note="G2/mitotic-specific cyclin-B"
FT                   /id="PRO_0000080388"
SQ   SEQUENCE   428 AA;  48285 MW;  CE89FAC0A41A35DE CRC64;
     MTTRAASANL ANARMMHNME EAGHMANLKG RPHTSHASQR NTLGDIGNQV SAITISDVPR
     KDPIIKKEIV HLSSHQHKIL TKSKATTSLK SLAEESHIPK KQEAFTFLEP VAAMPKPTTV
     PTATVLPQPT VPVPMDISEN VPESFSRVLL NVQNIDANDK ENPQLVSEYV NDIYDYMRDL
     EGKYPIRHNY LENQEITGKM RAILIDWLCQ VHHRFHLLQE TLYLTVAIID RLLQESPVPR
     NKLQLVGVTS MLIASKYEEM YAPEVADFVY ITDNAYTKKE ILEMEQHILK KLNFSFGRPL
     CLHFLRRDSK AGQVDANKHT LAKYLMELTI TEYDMVQYLP SKIAAAALCL SMKLLDSTHW
     TETLTHYSSY CEKDLVSTMQ KLASLVIKAE NSKLTAVHTK YSSSKFMKIS KLAALKSPLV
     KELAAASV