ID   CCNG1_PIG               Reviewed;         295 AA.
AC   Q52QT8;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Cyclin-G1;
GN   Name=CCNG1;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Skeletal muscle;
RA   Xu D.Q., Xiong Y.Z., Liu M.;
RT   "Molecular cloning and characterization of porcine CCNG1.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in growth regulation. Is associated with G2/M
CC       phase arrest in response to DNA damage. May be an intermediate by which
CC       p53 mediates its role as an inhibitor of cellular proliferation (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin G subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AY974246; AAX84681.1; -; mRNA.
DR   RefSeq; NP_001026951.1; NM_001031781.2.
DR   AlphaFoldDB; Q52QT8; -.
DR   SMR; Q52QT8; -.
DR   IntAct; Q52QT8; 1.
DR   STRING; 9823.ENSSSCP00000018036; -.
DR   PaxDb; Q52QT8; -.
DR   PRIDE; Q52QT8; -.
DR   Ensembl; ENSSSCT00005068631; ENSSSCP00005042706; ENSSSCG00005042723.
DR   Ensembl; ENSSSCT00015013429; ENSSSCP00015005194; ENSSSCG00015010126.
DR   Ensembl; ENSSSCT00025042033; ENSSSCP00025017891; ENSSSCG00025030659.
DR   Ensembl; ENSSSCT00030084818; ENSSSCP00030039054; ENSSSCG00030060617.
DR   Ensembl; ENSSSCT00035063959; ENSSSCP00035025894; ENSSSCG00035047997.
DR   Ensembl; ENSSSCT00040085558; ENSSSCP00040037440; ENSSSCG00040062448.
DR   Ensembl; ENSSSCT00045046642; ENSSSCP00045032372; ENSSSCG00045027306.
DR   Ensembl; ENSSSCT00050051912; ENSSSCP00050021805; ENSSSCG00050038477.
DR   Ensembl; ENSSSCT00055010025; ENSSSCP00055007924; ENSSSCG00055005093.
DR   Ensembl; ENSSSCT00060057552; ENSSSCP00060024620; ENSSSCG00060042428.
DR   Ensembl; ENSSSCT00065105619; ENSSSCP00065046879; ENSSSCG00065076429.
DR   Ensembl; ENSSSCT00070027020; ENSSSCP00070022463; ENSSSCG00070013834.
DR   Ensembl; ENSSSCT00070027029; ENSSSCP00070022472; ENSSSCG00070013834.
DR   GeneID; 595110; -.
DR   KEGG; ssc:595110; -.
DR   CTD; 900; -.
DR   eggNOG; KOG0653; Eukaryota.
DR   HOGENOM; CLU_062642_0_0_1; -.
DR   InParanoid; Q52QT8; -.
DR   OMA; CFEAQEE; -.
DR   OrthoDB; 1015714at2759; -.
DR   TreeFam; TF101007; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Chromosome 16.
DR   Genevisible; Q52QT8; SS.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR028860; CCNG1.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   PANTHER; PTHR10177:SF59; PTHR10177:SF59; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SUPFAM; SSF47954; SSF47954; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis; Nucleus; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Cyclin-G1"
FT                   /id="PRO_0000292656"
SQ   SEQUENCE   295 AA;  34020 MW;  C727798F8696C492 CRC64;
     MIEVPTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL
     SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSLE EERNVPLATD
     LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQESLP YERRNSLNFE
     RLEAQLKACY CRIIFSKAKP SVLALSIIAL EIQALKCVEL AEGAECLQKH SKINGRDLTF
     WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRITHLPTI PEMVP