ID   CCNG1_PONAB             Reviewed;         295 AA.
AC   Q5R5D0;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Cyclin-G1;
GN   Name=CCNG1; Synonyms=CCNG;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in growth regulation. Is associated with G2/M
CC       phase arrest in response to DNA damage. May be an intermediate by which
CC       p53 mediates its role as an inhibitor of cellular proliferation (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Note=DNA replication foci
CC       after DNA damage. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin G subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CR860932; CAH93036.1; -; mRNA.
DR   AlphaFoldDB; Q5R5D0; -.
DR   SMR; Q5R5D0; -.
DR   STRING; 9601.ENSPPYP00000017925; -.
DR   eggNOG; KOG0653; Eukaryota.
DR   InParanoid; Q5R5D0; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR028860; CCNG1.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   PANTHER; PTHR10177:SF59; PTHR10177:SF59; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SUPFAM; SSF47954; SSF47954; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cyclin; Mitosis; Nucleus; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Cyclin-G1"
FT                   /id="PRO_0000080467"
SQ   SEQUENCE   295 AA;  34047 MW;  2A10D40939E0ABFA CRC64;
     MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL
     SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE EERNVPLATD
     LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQENLP LERRNNINFE
     RLEAQLKACH CRIIFSKAKP SVLALSIIAL EIQAQKCVEL TEGIECLQKL SKINGRDLTF
     WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRIAHLPTI PEMVP