ID   CCNH_ECHMU              Reviewed;         335 AA.
AC   Q9GP34;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Probable cyclin-H;
GN   Name=CYCH;
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=H-95;
RX   PubMed=10973970; DOI=10.1074/jbc.m006091200;
RA   Brehm K., Jensen K., Frosch M.;
RT   "mRNA trans-splicing in the human parasitic cestode Echinococcus
RT   multilocularis.";
RL   J. Biol. Chem. 275:38311-38318(2000).
CC   -!- FUNCTION: Regulates CDK7, the catalytic subunit of the CDK-activating
CC       kinase (CAK) enzymatic complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin C subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AJ292374; CAC18548.1; -; mRNA.
DR   AlphaFoldDB; Q9GP34; -.
DR   SMR; Q9GP34; -.
DR   eggNOG; KOG2496; Eukaryota.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR043198; Cyclin/Ssn8.
DR   InterPro; IPR031658; Cyclin_C_2.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10026; PTHR10026; 1.
DR   Pfam; PF16899; Cyclin_C_2; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cyclin; Nucleus.
FT   CHAIN           1..335
FT                   /note="Probable cyclin-H"
FT                   /id="PRO_0000080475"
SQ   SEQUENCE   335 AA;  38678 MW;  B319DFE467F3CD2A CRC64;
     MAYVTSTQLY NWRFTQDELA NQRQECNAAV RRRLSAQYRA KAEVKGGDVP AEPTFLTAEE
     EFIIVKRYIF AMKELFHQFS DSGLPVDVFG FAATYLKRFY LNNSVMDYFP REMMLTALYL
     ACKAADYPLG LQTFAAHIPR NREHYSEIVV HSELFLMEKL QYDIWIHTPY RPLSGLLVDL
     LAYRKTQLGE PMTIEAGEVA TADMMTSLKK EGYEIIHKWF QTDLCLTHSP SQFALAVLLE
     LGQKHPDLGV EKFVKNSVCE YNSSDELMEQ KWTALNEKME QIQTMIGEFE FLSDLTYGSD
     LEAVLMQCRN PLYDPLSEEY AAAKEQAEKL MSFLD