ID   CCNJL_MOUSE             Reviewed;         387 AA.
AC   Q5SRT8; B2RTH5;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Cyclin-J-like protein;
GN   Name=Ccnjl; Synonyms=Gm877;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Eye;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin J subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AK143205; BAE25304.1; -; mRNA.
DR   EMBL; AL670472; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC139344; AAI39345.1; -; mRNA.
DR   EMBL; BC139345; AAI39346.1; -; mRNA.
DR   CCDS; CCDS24559.1; -.
DR   RefSeq; NP_001038995.1; NM_001045530.2.
DR   AlphaFoldDB; Q5SRT8; -.
DR   SMR; Q5SRT8; -.
DR   STRING; 10090.ENSMUSP00000058111; -.
DR   PhosphoSitePlus; Q5SRT8; -.
DR   PaxDb; Q5SRT8; -.
DR   PRIDE; Q5SRT8; -.
DR   Antibodypedia; 45857; 118 antibodies from 19 providers.
DR   Ensembl; ENSMUST00000050574; ENSMUSP00000058111; ENSMUSG00000044707.
DR   GeneID; 380694; -.
DR   KEGG; mmu:380694; -.
DR   UCSC; uc007ims.2; mouse.
DR   CTD; 79616; -.
DR   MGI; MGI:2685723; Ccnjl.
DR   VEuPathDB; HostDB:ENSMUSG00000044707; -.
DR   eggNOG; KOG0654; Eukaryota.
DR   GeneTree; ENSGT00940000159349; -.
DR   HOGENOM; CLU_063883_0_0_1; -.
DR   InParanoid; Q5SRT8; -.
DR   OMA; PAGCFDS; -.
DR   OrthoDB; 993640at2759; -.
DR   PhylomeDB; Q5SRT8; -.
DR   TreeFam; TF101009; -.
DR   BioGRID-ORCS; 380694; 2 hits in 72 CRISPR screens.
DR   ChiTaRS; Ccnjl; mouse.
DR   PRO; PR:Q5SRT8; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q5SRT8; protein.
DR   Bgee; ENSMUSG00000044707; Expressed in embryonic post-anal tail and 137 other tissues.
DR   Genevisible; Q5SRT8; MM.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   2: Evidence at transcript level;
KW   Cyclin; Reference proteome.
FT   CHAIN           1..387
FT                   /note="Cyclin-J-like protein"
FT                   /id="PRO_0000309320"
FT   DOMAIN          13..142
FT                   /note="Cyclin N-terminal"
SQ   SEQUENCE   387 AA;  43530 MW;  A0B989CFF99AC3E4 CRC64;
     MDEPWWEGRV ASDVHCTLRE KELKLPTFRA HSPLLKSRRF FVDILTLLSR HCHLCPSARH
     LAIYLLDHFM DQYNITTSKQ LYTVAVSCLL LASKFEDRED RVPKLEQINN TRILSSQNFS
     LTKKELLTTE LLLLEAFSWD LCLPTPAHFL DYYLLASISQ KDHHCHAWPT TCLRKTKECL
     KEYAHYFLEV TLQDHIFYKF QPSVVAAACV GASRICLQLS PYWTRDLQRV SSYSLEHLST
     CIEILLVAYD NVLKDAVAVK SQTLAMVPGS SSAPAQVLFQ PPTYPTLSQP PPTTLAQFQS
     PAQDLCLAYR DSLQAHRSGG LLSGDTGPSL HTPYPTLQPL DMCPVPVPAS LSMQMAIAAE
     PRHCLTASYG SSYFSGSHMF PAGCFDS