ID   CCNQ_RAT                Reviewed;         250 AA.
AC   Q4QQW5; Q5RJY7;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Cyclin-Q;
DE   AltName: Full=CDK10-activating cyclin;
DE   AltName: Full=Cyclin-M;
DE   AltName: Full=Cyclin-related protein FAM58A;
GN   Name=Ccnq; Synonyms=Fam58a;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary, and Spleen;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Activating cyclin for the cyclin-associated kinase CDK10.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Associates with CDK10 to promote its kinase activity.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC086445; AAH86445.1; -; mRNA.
DR   EMBL; BC097941; AAH97941.1; -; mRNA.
DR   RefSeq; NP_001020583.1; NM_001025412.1.
DR   AlphaFoldDB; Q4QQW5; -.
DR   SMR; Q4QQW5; -.
DR   STRING; 10116.ENSRNOP00000011019; -.
DR   iPTMnet; Q4QQW5; -.
DR   PhosphoSitePlus; Q4QQW5; -.
DR   PaxDb; Q4QQW5; -.
DR   Ensembl; ENSRNOT00000011019; ENSRNOP00000011019; ENSRNOG00000022582.
DR   GeneID; 303321; -.
DR   KEGG; rno:303321; -.
DR   CTD; 92002; -.
DR   RGD; 1305651; Ccnq.
DR   eggNOG; KOG0834; Eukaryota.
DR   GeneTree; ENSGT00940000155445; -.
DR   HOGENOM; CLU_022000_2_0_1; -.
DR   InParanoid; Q4QQW5; -.
DR   OMA; FDTHVAL; -.
DR   OrthoDB; 958680at2759; -.
DR   PhylomeDB; Q4QQW5; -.
DR   TreeFam; TF101013; -.
DR   PRO; PR:Q4QQW5; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000022582; Expressed in pancreas and 20 other tissues.
DR   Genevisible; Q4QQW5; RN.
DR   GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISO:RGD.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0030295; F:protein kinase activator activity; ISO:RGD.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISO:RGD.
DR   GO; GO:1902749; P:regulation of cell cycle G2/M phase transition; ISO:RGD.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR028759; Cyclin-Q.
DR   InterPro; IPR043198; Cyclin/Ssn8.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10026; PTHR10026; 1.
DR   PANTHER; PTHR10026:SF70; PTHR10026:SF70; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   2: Evidence at transcript level;
KW   Acetylation; Cyclin; Reference proteome.
FT   CHAIN           1..250
FT                   /note="Cyclin-Q"
FT                   /id="PRO_0000297569"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N1B3"
SQ   SEQUENCE   250 AA;  28947 MW;  6516414FD0D22BEB CRC64;
     MEAVRPDSCE RGTAAARAEE RPAPEARAHF RVTRFIMEAG VKLGMQSIPI ATACTIYHKF
     FCEINLDAYD LYLVAMSSLY LAGKVEEQHL RTRDIINVSH RYFNPGSEPL ELDSRFWELR
     DSIVQCELLM LRVLRFQVSF QHPHKYLLHY LISLKNWLNR YSWQRTPISV TAWALLRDSY
     HGGLCLRFQA QHLAVAVLYL ALQVYGVEVP AEGEAEKPWW QVFSDDLTKP IIDNIVSDLI
     QIYTMDTEIP