位置:首页 > 蛋白库 > CCPA_STAAW
CCPA_STAAW
ID   CCPA_STAAW              Reviewed;         329 AA.
AC   Q8NW33;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Catabolite control protein A;
GN   Name=ccpA; OrderedLocusNames=MW1679;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- FUNCTION: Global transcriptional regulator of carbon catabolite
CC       repression (CCR) and carbon catabolite activation (CCA), which ensures
CC       optimal energy usage under diverse conditions. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000033; BAB95544.1; -; Genomic_DNA.
DR   RefSeq; WP_000219066.1; NC_003923.1.
DR   AlphaFoldDB; Q8NW33; -.
DR   SMR; Q8NW33; -.
DR   EnsemblBacteria; BAB95544; BAB95544; BAB95544.
DR   KEGG; sam:MW1679; -.
DR   HOGENOM; CLU_037628_6_0_9; -.
DR   OMA; HSEFVFM; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR006377; CcpA.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   TIGRFAMs; TIGR01481; ccpA; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..329
FT                   /note="Catabolite control protein A"
FT                   /id="PRO_0000107931"
FT   DOMAIN          1..57
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        5..24
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   329 AA;  36060 MW;  1D5ACFD4F34C85B4 CRC64;
     MTVTIYDVAR EARVSMATVS RVVNGNQNVK AETKNKVNEV IKRLNYRPNA VARGLASKKT
     TTVGVIIPDI SNIYYSQLAR GLEDIATMYK YHSIISNSDN DPEKEKEIFN NLLSKQVDGI
     IFLGGTITEE MKELINQSSV PVVVSGTNGK DAHIASVNID FTEAAKEITG ELIEKGAKSF
     ALVGGEHSKK AQEDVLEGLT EVLNKNGLQL GDTLNCSGAE SYKEGVKAFA KMKGNLPDAI
     LCISDEEAIG IMHSAMDAGI KVPEELQIIS FNNTRLVEMV RPQLSSVIQP LYDIGAVGMR
     LLTKYMNDEK IEEPNVVLPH RIEYRGTTK
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024