CCS1_PHATC
ID CCS1_PHATC Reviewed; 420 AA.
AC A0T0G8; Q5D707;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Cytochrome c biogenesis protein Ccs1 {ECO:0000255|HAMAP-Rule:MF_01392};
GN Name=ccs1 {ECO:0000255|HAMAP-Rule:MF_01392};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OG Plastid; Chloroplast.
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1;
RX PubMed=17252281; DOI=10.1007/s00438-006-0199-4;
RA Oudot-Le Secq M.-P., Grimwood J., Shapiro H., Armbrust E.V., Bowler C.,
RA Green B.R.;
RT "Chloroplast genomes of the diatoms Phaeodactylum tricornutum and
RT Thalassiosira pseudonana: comparison with other plastid genomes of the red
RT lineage.";
RL Mol. Genet. Genomics 277:427-439(2007).
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000255|HAMAP-Rule:MF_01392}.
CC -!- SUBUNIT: May interact with CcsA. {ECO:0000255|HAMAP-Rule:MF_01392}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000255|HAMAP-Rule:MF_01392}; Multi-pass membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_01392}.
CC -!- SIMILARITY: Belongs to the Ccs1/CcsB family. {ECO:0000255|HAMAP-
CC Rule:MF_01392}.
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DR EMBL; EF067920; ABK20666.1; -; Genomic_DNA.
DR RefSeq; YP_874443.1; NC_008588.1.
DR AlphaFoldDB; A0T0G8; -.
DR STRING; 556484.A0T0G8; -.
DR GeneID; 4524566; -.
DR InParanoid; A0T0G8; -.
DR Proteomes; UP000000759; Chloroplast.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01392; CytC_Ccs1; 1.
DR InterPro; IPR023494; Cyt_c_bgen_Ccs1/CcsB/ResB.
DR InterPro; IPR007816; ResB-like_domain.
DR PANTHER; PTHR31566; PTHR31566; 1.
DR Pfam; PF05140; ResB; 2.
PE 3: Inferred from homology;
KW Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid;
KW Reference proteome; Thylakoid; Transmembrane; Transmembrane helix.
FT CHAIN 1..420
FT /note="Cytochrome c biogenesis protein Ccs1"
FT /id="PRO_0000363646"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01392"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01392"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01392"
FT VARIANT 65
FT /note="L -> F (in UTEX 646 / Bohlin)"
FT VARIANT 132
FT /note="R -> Q (in UTEX 646 / Bohlin)"
FT VARIANT 155
FT /note="G -> D (in UTEX 646 / Bohlin)"
FT VARIANT 282
FT /note="I -> T (in UTEX 646 / Bohlin)"
SQ SEQUENCE 420 AA; 48694 MW; D81B831078F8686E CRC64;
MKQQIFRLLA DLRFSIFLLL LISFCSIVGT VIEQDQSIEI YKTNYPLTNP VFGVLTWDRI
LLFGLDHVYR TWWFFALIFL FGLSLILCTF LQQLPSLKIA RRCQFFRTTN QFYRLKISTV
LNDFSFNKIL GRITGSQYSI FQQKNIVYCY KGLIGRIAPI LVHLSMILIL VGTIVGSLFG
FKAQEIVPKT ENFHIQNILA NGQLTVIPKT SARINDFWIT YTKTKTVSQF YSDISILNKQ
GNEIERKTIS VNHPLIHNGV YYYQTDWNLV GLRFKTMANE IIEYPLINFS ENQKIWLTWI
STNKSLTEGV VTIIDNLEGY CSIYNETGQF LGNIELNEII NLKQPLTLIE IISSTGLQIK
TDPGIQIIYS GFFFLMLSTL ISYITYSQIW IIQKEKKLFI GGTTNRAVFD FELEFFKIIK
