ID   CCSA_GLOC7              Reviewed;         328 AA.
AC   B7KA41;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   OrderedLocusNames=PCC7424_2995;
OS   Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS   7424)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX   NCBI_TaxID=65393;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424;
RX   PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; CP001291; ACK71397.1; -; Genomic_DNA.
DR   RefSeq; WP_015954994.1; NC_011729.1.
DR   AlphaFoldDB; B7KA41; -.
DR   SMR; B7KA41; -.
DR   STRING; 65393.PCC7424_2995; -.
DR   EnsemblBacteria; ACK71397; ACK71397; PCC7424_2995.
DR   KEGG; cyc:PCC7424_2995; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_049710_2_4_3; -.
DR   OMA; WLVMHVS; -.
DR   OrthoDB; 955123at2; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Cytochrome c-type biogenesis; Membrane; Reference proteome; Thylakoid;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_1000145248"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        297..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   328 AA;  35362 MW;  F937906083549820 CRC64;
     MNLVNLENIL DNTSFLVLFL TMMIYWVGAA FPSVPYLQAL GTAGVAIANL CIAALLGARW
     IEAGYFPISN LYESLFFLAW GVTAAHLIAQ QMSRSHLVGV VTTPVAMGIS AFAALTLPAD
     MQTSAPLVPA LKSNWLMMHV SVMMLSYATL MVGSALAIAF LFVTKGQNVE LHGSSVGTGG
     YRTGVRLNKP QPVQETAIEG SGNVAVLNTT VVSDAPSLSL QRLSIADTLD NISYRIIGLG
     FPLLTIGIIA GAVWANEAWG SYWSWDPKET WALITWLVFA AYLHARITKG WQGRKPAILA
     ASGFVVVWVC YLGVNLLGKG LHSYGWFF