ID   CCSA_HETA2              Reviewed;         322 AA.
AC   B2XT99;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   OrderedLocusNames=Heak293_Cp090;
OS   Heterosigma akashiwo (strain NIES-293 / 8280G21-1).
OG   Plastid; Chloroplast.
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Raphidophyceae; Chattonellales;
OC   Chattonellaceae; Heterosigma.
OX   NCBI_TaxID=536047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18462506; DOI=10.1186/1471-2164-9-211;
RA   Cattolico R.A., Jacobs M.A., Zhou Y., Chang J., Duplessis M., Lybrand T.,
RA   McKay J., Ong H.C., Sims E., Rocap G.;
RT   "Chloroplast genome sequencing analysis of Heterosigma akashiwo CCMP452
RT   (West Atlantic) and NIES293 (West Pacific) strains.";
RL   BMC Genomics 9:211-211(2008).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with Ccs1. {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01391}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; EU168190; ABV65997.1; -; Genomic_DNA.
DR   RefSeq; YP_001936391.1; NC_010772.1.
DR   AlphaFoldDB; B2XT99; -.
DR   SMR; B2XT99; -.
DR   GeneID; 6335543; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid; Thylakoid;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..322
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353795"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        264..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   322 AA;  37094 MW;  48055F8E28109DC3 CRC64;
     MHTSIVTLNL DAYQNFLANA IFCNLLLTMC LYWFSLIIVN NNLICNLAKF SAVNSNVILF
     FYLSWRWYNY NFFPLSNLYE SLMFLSCLLL FIYQFIEFKT RSRVIGALVL PLIVLVQGFA
     SLSLPTAMQK SSPLVPALQS NWLMLHVSMM MLSYATLLLG SLFSILYLVL YKDKKILTKK
     SIKEQFVEEN FVFQLTTSAF SLNQTSNIIT EAKTDRQRLI LSLDNWSYRT IGIGFPFLTM
     GIISGAVWAN EAWGSYWSWD PKETWALITW LIFASYLHAR LTKGWRGKRA AFLGSFGFFI
     VWVCYLGVNF LGKGLHSYGF LN