CCSA_NOSS1
ID CCSA_NOSS1 Reviewed; 351 AA.
AC Q8YYB4;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391}; OrderedLocusNames=all0936;
OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=103690;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT "Complete genomic sequence of the filamentous nitrogen-fixing
RT cyanobacterium Anabaena sp. strain PCC 7120.";
RL DNA Res. 8:205-213(2001).
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01391}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR EMBL; BA000019; BAB72893.1; -; Genomic_DNA.
DR PIR; AE1923; AE1923.
DR RefSeq; WP_010995110.1; NZ_RSCN01000006.1.
DR AlphaFoldDB; Q8YYB4; -.
DR SMR; Q8YYB4; -.
DR STRING; 103690.17130282; -.
DR EnsemblBacteria; BAB72893; BAB72893; BAB72893.
DR KEGG; ana:all0936; -.
DR eggNOG; COG0755; Bacteria.
DR OMA; WLVMHVS; -.
DR OrthoDB; 955123at2; -.
DR Proteomes; UP000002483; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR PANTHER; PTHR30071; PTHR30071; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE 3: Inferred from homology;
KW Cytochrome c-type biogenesis; Membrane; Reference proteome; Thylakoid;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..351
FT /note="Cytochrome c biogenesis protein CcsA"
FT /id="PRO_0000353697"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ SEQUENCE 351 AA; 38159 MW; 9C05A16D344E8539 CRC64;
MNLVSLQNWL DNASFAVLFL TMLLYWIGAA FPGLPAINAL GTAGMAIANL SIATLLGARW
IEAGYFPLSN LYESLFFLSW GITTVHLIAE NSSRSRLVGV FTTPVAMGIV AFATLTLPSD
MQVSEPLVPA LKSNWLMMHV SVMMLSYSAL MVGSLLAIAF LVITRGNNIQ LQGSSVGNGG
YRTNGYRLMK AGELVSQPAT PPVENNGFTR LESQNNGNSN TAVLNLATTP QTPTLTSTET
LSPQRLSLAE TLDNISYRII GLGFPLLTIG IIAGAVWANE AWGSYWSWDP KETWALITWL
VFAAYLHARI TRGWQGRRPA ILAASGFVVV WICYLGVNLL GKGLHSYGWF F