CCSA_NUPAD
ID CCSA_NUPAD Reviewed; 308 AA.
AC Q4FGG2;
DT 04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 03-AUG-2022, entry version 49.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
OS Nuphar advena (Common spatterdock) (Nuphar lutea subsp. advena).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Nymphaeales; Nymphaeaceae; Nuphar.
OX NCBI_TaxID=77108;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX PubMed=15944438; DOI=10.1093/molbev/msi191;
RA Leebens-Mack J., Raubeson L.A., Cui L., Kuehl J.V., Fourcade M.H.,
RA Chumley T.W., Boore J.L., Jansen R.K., dePamphilis C.W.;
RT "Identifying the basal angiosperm node in chloroplast genome phylogenies:
RT sampling one's way out of the Felsenstein zone.";
RL Mol. Biol. Evol. 22:1948-1963(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17573971; DOI=10.1186/1471-2164-8-174;
RA Raubeson L.A., Peery R., Chumley T.W., Dziubek C., Fourcade H.M.,
RA Boore J.L., Jansen R.K.;
RT "Comparative chloroplast genomics: analyses including new sequences from
RT the angiosperms Nuphar advena and Ranunculus macranthus.";
RL BMC Genomics 8:174-174(2007).
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with Ccs1. {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000255|HAMAP-Rule:MF_01391}; Multi-pass membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR EMBL; DQ069369; AAZ03813.1; -; Genomic_DNA.
DR EMBL; DQ354691; ABC60508.1; -; Genomic_DNA.
DR RefSeq; YP_001001583.1; NC_008788.1.
DR AlphaFoldDB; Q4FGG2; -.
DR SMR; Q4FGG2; -.
DR GeneID; 4699563; -.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR PANTHER; PTHR30071; PTHR30071; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE 3: Inferred from homology;
KW Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid; Thylakoid;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..308
FT /note="Cytochrome c biogenesis protein CcsA"
FT /id="PRO_0000353774"
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 246..260
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ SEQUENCE 308 AA; 35080 MW; A36844F54A09D427 CRC64;
MIFATLEHIL THISFSIISI VIPTHLMTSV YEIVGLCDLS EKGMIATFFC ITGLLVTRWI
YSGHVPLSDL YESLMFLSWS FSFIHIVPYF RNYKNYFSTI TAPSAILTQG FATSGLLTKM
HQSAILVPAL QSRWLMMHVS MMLLSYAALL CGSLLSITLL VITFRRNIDI IGKTNHLLIS
SFSFDEIQYL NVSFRNYHRY QLTQRLDHWS YRVIGLGFTL LTIGILSGAV WANEAWGSYW
NWDPKETWAF ITWTVFAIYS HTRTNKSLQG ANSAIVASIG FLIIWICYFG VNLLGRGLHS
YGSFTLNI