ID   CCSA_PROM2              Reviewed;         309 AA.
AC   A8G4E3;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391}; OrderedLocusNames=P9215_08591;
OS   Prochlorococcus marinus (strain MIT 9215).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=93060;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9215;
RX   PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA   Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA   Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA   Richardson P., Chisholm S.W.;
RT   "Patterns and implications of gene gain and loss in the evolution of
RT   Prochlorococcus.";
RL   PLoS Genet. 3:2515-2528(2007).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; CP000825; ABV50474.1; -; Genomic_DNA.
DR   RefSeq; WP_012007574.1; NC_009840.1.
DR   AlphaFoldDB; A8G4E3; -.
DR   SMR; A8G4E3; -.
DR   STRING; 93060.P9215_08591; -.
DR   EnsemblBacteria; ABV50474; ABV50474; P9215_08591.
DR   KEGG; pmh:P9215_08591; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_049710_2_4_3; -.
DR   OMA; WLVMHVS; -.
DR   OrthoDB; 955123at2; -.
DR   Proteomes; UP000002014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Cytochrome c-type biogenesis; Membrane; Thylakoid; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353706"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        250..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   309 AA;  34915 MW;  772AB7140CAEDCBB CRC64;
     MILENLFKNL IYDPVSVLGL LVFYILLVNL PISLGAFFQK KSFFIVRVLT ILINFLITLQ
     LLFRWSISGH FPISNLYESL YFLTWGITMG QLLIEREYQS PIIPSIAIPI ELLTVAFACF
     VLPDDLKISS NLVPALRSSW LVMHVSVVML SYAALIIGSL LSASVLFINK NKPLQIRSSS
     TGIGGFKISN NYPLNELVEP IEFSHSEELD TLSYRSILIG FVLLTLGLIS GAVWANEAWG
     TWWSWDPKET WAFISWMFYA AYLHMRISKG WQGRRPALLA TTGFLVVLIC YLGVNFLGIG
     LHSYGWIFG