ID   CCSA_PROMP              Reviewed;         314 AA.
AC   Q7V1U0;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391}; OrderedLocusNames=PMM0765;
OS   Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 /
OS   MED4).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59919;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1986 / NIES-2087 / MED4;
RX   PubMed=12917642; DOI=10.1038/nature01947;
RA   Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA   Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA   Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA   Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA   Chisholm S.W.;
RT   "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT   differentiation.";
RL   Nature 424:1042-1047(2003).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; BX548174; CAE19224.1; -; Genomic_DNA.
DR   RefSeq; WP_011132399.1; NC_005072.1.
DR   AlphaFoldDB; Q7V1U0; -.
DR   SMR; Q7V1U0; -.
DR   STRING; 59919.PMM0765; -.
DR   EnsemblBacteria; CAE19224; CAE19224; PMM0765.
DR   KEGG; pmm:PMM0765; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_049710_2_4_3; -.
DR   OMA; WLVMHVS; -.
DR   OrthoDB; 955123at2; -.
DR   Proteomes; UP000001026; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Cytochrome c-type biogenesis; Membrane; Thylakoid; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353712"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        250..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   314 AA;  35442 MW;  F68BD895BF9136FB CRC64;
     MIFDGFIKNF IYDPVSFIGI LIFYFLLINL PISLISLFNK KSSSYVRLIT ILINLFIALQ
     LISRWIISGH FPISNLYESL YFLVWGITLG QLLIEKEYST PIIPAIAIPI ELLTIAFACF
     VLPEDLKLSS NLVPALRSSW LVMHVSVVML SYAALIMGSL LSASVLFINN SQPLQLRSSS
     MGVGGFKISN SYSTNNVIEP INFSHSEELD TLSYRSILVG FVLLTLGLIT GAIWANEAWG
     TWWSWDPKET WAFISWLFYA AYLHMRISRG WQGRRPALLA TSGFFVVLIC YIGVNFLGVG
     LHSYGWIFGI FNLF