ID   CCSA_RIPO1              Reviewed;         341 AA.
AC   B7K1C1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   OrderedLocusNames=PCC8801_2297;
OS   Rippkaea orientalis (strain PCC 8801) (Cyanothece sp. (strain PCC 8801)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801;
RX   PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; CP001287; ACK66316.1; -; Genomic_DNA.
DR   RefSeq; WP_012595584.1; NC_011726.1.
DR   AlphaFoldDB; B7K1C1; -.
DR   SMR; B7K1C1; -.
DR   STRING; 41431.PCC8801_2297; -.
DR   EnsemblBacteria; ACK66316; ACK66316; PCC8801_2297.
DR   KEGG; cyp:PCC8801_2297; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_049710_2_4_3; -.
DR   OMA; WLVMHVS; -.
DR   OrthoDB; 955123at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Cytochrome c-type biogenesis; Membrane; Reference proteome; Thylakoid;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_1000145249"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   341 AA;  36776 MW;  DDD34B53A634BB28 CRC64;
     MNLITLENFL DNSSFLILLL TMLIYWAGAA FPGMSILPTL GTAGVAIANL SIATLLGSRW
     LEGGYFPLSN LYESLFFLAW GVTAVHLIAE KMSRSTLVGV VTTPVAMGIT AFAALSLPAD
     MQTSAPLVPA LKSNWLMMHV SVMMLSYATL MVGAVLAIAF LIVTRGQDVE LRGSSVGTGS
     YRNKLGRIQL SQAEKTPDGS VVAMADGNGS VGTAVLDRVD PQTLVTDLPN LSPQRLNLAD
     TLDNISYRII GLGFPLLTIG IIAGAVWANE AWGSYWSWDP KETWALITWL VFAAYLHARI
     TRGWQGRKPA ILAASGFIVV WVCYLGVNLL GKGLHSYGWF F