ID   CCSA_SORBI              Reviewed;         321 AA.
AC   A1E9X3;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623;
RX   PubMed=17534593; DOI=10.1007/s00122-007-0567-4;
RA   Saski C., Lee S.-B., Fjellheim S., Guda C., Jansen R.K., Luo H.,
RA   Tomkins J., Rognli O.A., Daniell H., Clarke J.L.;
RT   "Complete chloroplast genome sequences of Hordeum vulgare, Sorghum bicolor
RT   and Agrostis stolonifera, and comparative analyses with other grass
RT   genomes.";
RL   Theor. Appl. Genet. 115:571-590(2007).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with Ccs1. {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01391}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; EF115542; ABK79545.1; -; Genomic_DNA.
DR   RefSeq; YP_899456.1; NC_008602.1.
DR   AlphaFoldDB; A1E9X3; -.
DR   SMR; A1E9X3; -.
DR   STRING; 4558.Sb02g017866.1; -.
DR   GeneID; 4549151; -.
DR   KEGG; sbi:4549151; -.
DR   eggNOG; ENOG502QU0T; Eukaryota.
DR   InParanoid; A1E9X3; -.
DR   OrthoDB; 1361264at2759; -.
DR   Proteomes; UP000000768; Chloroplast.
DR   ExpressionAtlas; A1E9X3; baseline.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid;
KW   Reference proteome; Thylakoid; Transmembrane; Transmembrane helix.
FT   CHAIN           1..321
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353791"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        259..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   321 AA;  36625 MW;  C74DA65247EE20A5 CRC64;
     MLFATLEHIL THISFSTISI VITIHLITLL VRELRGLRDS SEKGMIATFF SITGFLVSRW
     VSSGHFPLSN LYESLIFLSW TLYILHTIPK IQNSKNDLST ITTPSTILTQ GFATSGLLTE
     MHQSTILVPA LQSQWLMMHV SMMLLSYATL LCGSLLSAAL LIIRFRNSFD FFSLKKNVFL
     KTFFFSEIEY LYAKRSALKN TSFPVFPNYY KYQLTERLDS WSYRVISLGF TLLTVGILCG
     AVWANEAWGS YWNWDPKETW AFITWTIFAI YLHSRTNPNW KGTNSALVAS IGFLIIWICY
     FGINLLGIGL HSYGSFTLPS K