CCSA_SPIOL
ID CCSA_SPIOL Reviewed; 323 AA.
AC Q9M3J1;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
OS Spinacia oleracea (Spinach).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC Caryophyllales; Chenopodiaceae; Chenopodioideae; Anserineae; Spinacia.
OX NCBI_TaxID=3562;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Geant d'hiver, and cv. Monatol;
RX PubMed=11292076; DOI=10.1023/a:1006478403810;
RA Schmitz-Linneweber C., Maier R.M., Alcaraz J.-P., Cottet A., Herrmann R.G.,
RA Mache R.;
RT "The plastid chromosome of spinach (Spinacia oleracea): complete nucleotide
RT sequence and gene organization.";
RL Plant Mol. Biol. 45:307-315(2001).
CC -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC c6 and cytochrome f) at the step of heme attachment.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SUBUNIT: May interact with Ccs1. {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC {ECO:0000255|HAMAP-Rule:MF_01391}; Multi-pass membrane protein
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR EMBL; AJ400848; CAB88783.1; -; Genomic_DNA.
DR RefSeq; NP_054987.1; NC_002202.1.
DR AlphaFoldDB; Q9M3J1; -.
DR SMR; Q9M3J1; -.
DR STRING; 3562.Q9M3J1; -.
DR GeneID; 2715692; -.
DR KEGG; soe:2715692; -.
DR OrthoDB; 1361264at2759; -.
DR Proteomes; UP000054095; Chloroplast.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01391; CytC_CcsA; 1.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR PANTHER; PTHR30071; PTHR30071; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE 3: Inferred from homology;
KW Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid;
KW Reference proteome; Thylakoid; Transmembrane; Transmembrane helix.
FT CHAIN 1..323
FT /note="Cytochrome c biogenesis protein CcsA"
FT /id="PRO_0000201617"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ SEQUENCE 323 AA; 36994 MW; 55D28A1797D4A9F3 CRC64;
MIFSTLEHIL THISFSTVSV VITLHLITLL VNEIVGLYNS LEKGMLVTFF CITGLLVTRW
VYWKHFPLSD LYESLIFLSW SFYLIHMIPS FLKKEKNSLN VITAPSAIFT QGFATSGLLT
EMHQSGILVP ALQSQWLMMH VSMMVLGYAA LLGGSLLSVT LLIIIFQKDL IQVFDKRKHL
LNESFFFGEI QYINEKSNIV QNASPSYVRN YYRSQLIEQL DHWSYRVISL GFIFLTIGIL
SGAVWANEAW GSYWNWDPKE TWAFITWTIF AIYLHIRTNK NLRGANSAIV AFIGFLIIWI
CYFGVNLLGI GLHSYGSFTL TLN