ID   CCSA_SYNS3              Reviewed;         305 AA.
AC   Q0IAM4;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391}; OrderedLocusNames=sync_1290;
OS   Synechococcus sp. (strain CC9311).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=64471;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9311;
RX   PubMed=16938853; DOI=10.1073/pnas.0602963103;
RA   Palenik B., Ren Q., Dupont C.L., Myers G.S., Heidelberg J.F., Badger J.H.,
RA   Madupu R., Nelson W.C., Brinkac L.M., Dodson R.J., Durkin A.S.,
RA   Daugherty S.C., Sullivan S.A., Khouri H., Mohamoud Y., Halpin R.,
RA   Paulsen I.T.;
RT   "Genome sequence of Synechococcus CC9311: insights into adaptation to a
RT   coastal environment.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:13555-13559(2006).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with ccs1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01391}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; CP000435; ABI47316.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q0IAM4; -.
DR   SMR; Q0IAM4; -.
DR   STRING; 64471.sync_1290; -.
DR   EnsemblBacteria; ABI47316; ABI47316; sync_1290.
DR   KEGG; syg:sync_1290; -.
DR   eggNOG; COG0755; Bacteria.
DR   HOGENOM; CLU_049710_2_4_3; -.
DR   OMA; WLVMHVS; -.
DR   Proteomes; UP000001961; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Cytochrome c-type biogenesis; Membrane; Reference proteome; Thylakoid;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..305
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353717"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        246..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   305 AA;  32928 MW;  CE5CA22445B89E5E CRC64;
     MDPVLGLGLF AFALLLLALP LAFWKVSSEK TSGLVTLLIA TANLALTAQL VLRWWQSGHF
     PISNLYESLC FLAWACTLTQ LLVERSWPTP IVAAAATPMG LGCIAFASFA LPDQLQEASP
     LVPALRSSWL VMHVSVIMVS YAALLVGSLL SVAVLVTDRG HALELRSSSI GSGGYRRAAL
     ATPLGNVGDS EVQLSSVKFT RNELLDSLSY RTITVGFLLL TVGIISGAVW ANEAWGSYWS
     WDPKETWALI CWLVYAAYLH TRLSRGWQGR RPALVASAGL VVIGVCYIGV NLLGIGLHSY
     GWFFG