ID   CCSA_TRACE              Reviewed;         316 AA.
AC   A9QCA0;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Cytochrome c biogenesis protein CcsA {ECO:0000255|HAMAP-Rule:MF_01391};
GN   Name=ccsA {ECO:0000255|HAMAP-Rule:MF_01391};
OS   Trachelium caeruleum (Blue throatwort).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Campanulaceae; Trachelium.
OX   NCBI_TaxID=28494;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=18048330; DOI=10.1073/pnas.0709121104;
RA   Jansen R.K., Cai Z., Raubeson L.A., Daniell H., dePamphilis C.W.,
RA   Leebens-Mack J., Muller K.F., Guisinger-Bellian M., Haberle R.C.,
RA   Hansen A.K., Chumley T.W., Lee S.B., Peery R., McNeal J.R., Kuehl J.V.,
RA   Boore J.L.;
RT   "Analysis of 81 genes from 64 plastid genomes resolves relationships in
RT   angiosperms and identifies genome-scale evolutionary patterns.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:19369-19374(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18330485; DOI=10.1007/s00239-008-9086-4;
RA   Haberle R.C., Fourcade H.M., Boore J.L., Jansen R.K.;
RT   "Extensive rearrangements in the chloroplast genome of Trachelium caeruleum
RT   are associated with repeats and tRNA genes.";
RL   J. Mol. Evol. 66:350-361(2008).
CC   -!- FUNCTION: Required during biogenesis of c-type cytochromes (cytochrome
CC       c6 and cytochrome f) at the step of heme attachment.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBUNIT: May interact with Ccs1. {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_01391}; Multi-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
CC   -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01391}.
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DR   EMBL; EU017286; ABU85693.1; -; Genomic_DNA.
DR   EMBL; EU090187; ABV26533.1; -; Genomic_DNA.
DR   RefSeq; YP_001718708.1; NC_010442.1.
DR   AlphaFoldDB; A9QCA0; -.
DR   SMR; A9QCA0; -.
DR   GeneID; 6155908; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01391; CytC_CcsA; 1.
DR   InterPro; IPR002541; Cyt_c_assembly.
DR   InterPro; IPR017562; Cyt_c_biogenesis_CcsA.
DR   InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR   PANTHER; PTHR30071; PTHR30071; 1.
DR   Pfam; PF01578; Cytochrom_C_asm; 1.
DR   TIGRFAMs; TIGR03144; cytochr_II_ccsB; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Cytochrome c-type biogenesis; Membrane; Plastid; Thylakoid;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..316
FT                   /note="Cytochrome c biogenesis protein CcsA"
FT                   /id="PRO_0000353792"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01391"
SQ   SEQUENCE   316 AA;  36174 MW;  8AC67A1A071DC978 CRC64;
     MKFSTLEHIL IHLSFSICSI VITIRLINLV VTTILKPYDF SEKGIITTFL CLTGFLVTRW
     IYSGHFPLSN LYESLIFLSW SFSLIHIVAY LKKNKNLSRI TASSTIFTQG FATSGLLTEI
     NKSGILVPAL QSEWLIMHVS MMILSYAALL CGSLLSAALL VITCRKKFNE LLRLIESLSF
     DKIQYRNQRI HLFGKTYFFS VKNYYKIQLV QQLDYWSYRV ISLGFIFLTM GILSGAVWAN
     EAWGSYWSWD PKETWAFITW IIFAIYLHTR TNKNFWGANS AIVAVIGFLI IWICYFGVNL
     LGIGLHSYGS FKGMAS