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CCT12_ORYSJ
ID   CCT12_ORYSJ             Reviewed;         630 AA.
AC   Q6Z7H3; B7F0D1; Q6Z7H4;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Cyclin-T1-2;
DE            Short=CycT1;2;
GN   Name=CYCT1_2; OrderedLocusNames=Os02g0438200, LOC_Os02g24190;
GN   ORFNames=OJ1570_H12.4-1, OJ1570_H12.4-2,
GN   OsJ_06547 {ECO:0000312|EMBL:EEE56895.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA   La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA   Ramachandran S.;
RT   "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL   Mol. Genet. Genomics 275:374-386(2006).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q6Z7H3-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q6Z7H3-2; Sequence=VSP_025287, VSP_025288;
CC   -!- SIMILARITY: Belongs to the cyclin family. Cyclin T subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP004856; BAD17159.1; -; Genomic_DNA.
DR   EMBL; AP004856; BAD17160.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF08654.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS78472.1; -; Genomic_DNA.
DR   EMBL; CM000139; EEE56895.1; -; Genomic_DNA.
DR   EMBL; AK102728; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK107537; BAG98078.1; -; mRNA.
DR   RefSeq; XP_015626103.1; XM_015770617.1. [Q6Z7H3-1]
DR   RefSeq; XP_015626104.1; XM_015770618.1. [Q6Z7H3-1]
DR   RefSeq; XP_015626105.1; XM_015770619.1.
DR   AlphaFoldDB; Q6Z7H3; -.
DR   SMR; Q6Z7H3; -.
DR   STRING; 4530.OS02T0438200-01; -.
DR   PaxDb; Q6Z7H3; -.
DR   PRIDE; Q6Z7H3; -.
DR   EnsemblPlants; Os02t0438200-01; Os02t0438200-01; Os02g0438200. [Q6Z7H3-1]
DR   GeneID; 4329229; -.
DR   Gramene; Os02t0438200-01; Os02t0438200-01; Os02g0438200. [Q6Z7H3-1]
DR   KEGG; osa:4329229; -.
DR   eggNOG; KOG0834; Eukaryota.
DR   HOGENOM; CLU_022000_8_2_1; -.
DR   InParanoid; Q6Z7H3; -.
DR   OMA; DHLCVER; -.
DR   OrthoDB; 1437076at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   ExpressionAtlas; Q6Z7H3; baseline and differential.
DR   Genevisible; Q6Z7H3; OS.
DR   GO; GO:0008024; C:cyclin/CDK positive transcription elongation factor complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061575; F:cyclin-dependent protein serine/threonine kinase activator activity; IBA:GO_Central.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00043; CYCLIN; 2.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR043198; Cyclin/Ssn8.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10026; PTHR10026; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   SMART; SM00385; CYCLIN; 2.
DR   SUPFAM; SSF47954; SSF47954; 2.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Cyclin; Reference proteome.
FT   CHAIN           1..630
FT                   /note="Cyclin-T1-2"
FT                   /id="PRO_0000287059"
FT   REGION          288..313
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          410..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..311
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..147
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_025287"
FT   VAR_SEQ         148..164
FT                   /note="RLVLTTVRFDFNIQHPY -> MEQCTGGTQLQLEESTR (in isoform
FT                   2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_025288"
SQ   SEQUENCE   630 AA;  71035 MW;  5B93CCAB67116E93 CRC64;
     MDGESQTSKL SCEHMYSWYF TREELEKFSP SRKDGITEIM ESEIRQLYCS FIRDVGIRLK
     LPQMTIATAI MFCHRFYLYQ SLAKNGWQTI ATVCIFLASK VEDTPCPLDQ VIRVAYGTMY
     RRDPATARRI HQKDVFEKQK ALILTGERLV LTTVRFDFNI QHPYRPLLDA MEKLGISQKE
     VKQVAWNFVN DWLKTTLCLQ YKPQYIAAGS LYLAAKFQNV KLPVHGGHVW WHQFDVAPKP
     LEAVLQQMRE MVHMKAKLFA HPSPAKQKEV LFEGMLLISN SPDSVLTQSS LSVSSSSPEI
     GDPNDHLQVD SSQDIVHIED RSKSYPERNL SNLTADMNNP GKTHNKESLD QALKIKHGGL
     ISCNQQIPLD AIAKIDSSTA KCVEQNIGIC CSSSNTFNGK ILNPFSISQR SGDKTKLCSE
     GGSSLTDVDS KSTQSVEPPT TICNHTSDSL NVDSLCSDQR LANSTAGTTE KASFVLPVQI
     KVDHLCVERK KVDVARIKDL LMKRKRRRER QGRCIPSVDL SEEAWIEREL ESGIVFKKVD
     HVVASYDLSD EGWIERELES GIVIGQKNDQ PVSLDGLTED DWIERELESG IIVEPGPAGK
     KLKSKLLSEG HEIMNSRWEI NGKSMQNQVT
 
 
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