CCT15_ARATH
ID CCT15_ARATH Reviewed; 579 AA.
AC Q9FKE6;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 2.
DT 25-MAY-2022, entry version 127.
DE RecName: Full=Cyclin-T1-5;
DE Short=CycT1;5;
DE AltName: Full=Protein AtCycT-like1;
GN Name=CYCT1-5; OrderedLocusNames=At5g45190; ORFNames=K18C1.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FKE6-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin T subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK227273; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB11392.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB012240; BAB11392.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95214.1; -; Genomic_DNA.
DR EMBL; AK227273; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_199332.2; NM_123887.4. [Q9FKE6-1]
DR AlphaFoldDB; Q9FKE6; -.
DR SMR; Q9FKE6; -.
DR BioGRID; 19804; 3.
DR STRING; 3702.AT5G45190.2; -.
DR iPTMnet; Q9FKE6; -.
DR PaxDb; Q9FKE6; -.
DR PRIDE; Q9FKE6; -.
DR EnsemblPlants; AT5G45190.1; AT5G45190.1; AT5G45190. [Q9FKE6-1]
DR GeneID; 834555; -.
DR Gramene; AT5G45190.1; AT5G45190.1; AT5G45190. [Q9FKE6-1]
DR KEGG; ath:AT5G45190; -.
DR Araport; AT5G45190; -.
DR eggNOG; KOG0834; Eukaryota.
DR HOGENOM; CLU_022000_8_1_1; -.
DR InParanoid; Q9FKE6; -.
DR PhylomeDB; Q9FKE6; -.
DR PRO; PR:Q9FKE6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FKE6; baseline and differential.
DR Genevisible; Q9FKE6; AT.
DR GO; GO:0008024; C:cyclin/CDK positive transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061575; F:cyclin-dependent protein serine/threonine kinase activator activity; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026; PTHR10026; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; SSF47954; 2.
PE 1: Evidence at protein level;
KW Alternative splicing; Cell cycle; Cell division; Cyclin; Phosphoprotein;
KW Reference proteome.
FT CHAIN 1..579
FT /note="Cyclin-T1-5"
FT /id="PRO_0000287057"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..579
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 423
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8GYM6"
SQ SEQUENCE 579 AA; 65187 MW; 8496BA1E68FA3EEB CRC64;
MAGVLAGECS YSESGVSSHS RNSHEKQEEV SRWYFGRKEI EENSPSRLDG IDLKKETYLR
KSYCTFLQDL GMRLKVPQVT IATAIIFCHR FFFRQSHAKN DRRTIATVCM FLAGKVEETP
RPLKDVIFVS YEIINKKDPG ASQKIKQKEV YEQQKELILN GEKIVLSTLG FDLNVYHPYK
PLVEAIKKFK VAQNALAQVA WNFVNDGLRT SLCLQFKPHH IAAGAIFLAA KFLKVKLPSD
GEKVWWQEFD VTPRQLEDVS NQMLELYEQN RVPASQGSEV ESSVGGGSAQ RPGSRNAVST
DEHVGSRQTS SVRSTHEQSN SDNHGGSSKG VLNQNNENGG GEAANVSVDN KEEIERETKE
SSLHLESHPA HKDNVREAPH NSRPLVEGPG KDNSEREGGE LQDDGAVHKS RNVDVGDALI
SQSPKDLKLL RDKVKAKREK AKKLLGERTR KKDLMDEDDL IERELEDVQL AVEDEKTKER
KVQSRPKAEN SDLMGTEHGE ILDVKGEVKN TEEGEMVNNN VSPMMHSRKR KMGSPPEKQS
EGKRRHNSEN GEESHKTSRG SSHHGDREHR RHSQENNHS
