CCU21_ARATH
ID CCU21_ARATH Reviewed; 222 AA.
AC Q9SHD3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Cyclin-U2-1;
DE Short=CycU2;1;
DE AltName: Full=Cyclin-P3.1;
DE Short=CycP3;1;
GN Name=CYCU2-1; OrderedLocusNames=At2g45080; ORFNames=T14P1.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP TISSUE SPECIFICITY, AND INTERACTION WITH CDKA-1.
RX PubMed=15197472; DOI=10.1007/s00018-004-4057-4;
RA Torres Acosta J.A., de Almeida Engler J., Raes J., Magyar Z., de Groodt R.,
RA Inze D., de Veylder L.;
RT "Molecular characterization of Arabidopsis PHO80-like proteins, a novel
RT class of CDKA;1-interacting cyclins.";
RL Cell. Mol. Life Sci. 61:1485-1497(2004).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
CC -!- SUBUNIT: Interacts with CDKA-1. {ECO:0000269|PubMed:15197472}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and flowers. Expressed in
CC the shoot apex, leaf primordia and young leaves.
CC {ECO:0000269|PubMed:15197472}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin U/P subfamily.
CC {ECO:0000305}.
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DR EMBL; CP002685; AEC10506.1; -; Genomic_DNA.
DR EMBL; AY074650; AAL69466.1; -; mRNA.
DR PIR; C84886; C84886.
DR RefSeq; NP_182034.1; NM_130072.3.
DR AlphaFoldDB; Q9SHD3; -.
DR SMR; Q9SHD3; -.
DR BioGRID; 4451; 1.
DR IntAct; Q9SHD3; 1.
DR STRING; 3702.AT2G45080.1; -.
DR PaxDb; Q9SHD3; -.
DR PRIDE; Q9SHD3; -.
DR EnsemblPlants; AT2G45080.1; AT2G45080.1; AT2G45080.
DR GeneID; 819115; -.
DR Gramene; AT2G45080.1; AT2G45080.1; AT2G45080.
DR KEGG; ath:AT2G45080; -.
DR Araport; AT2G45080; -.
DR TAIR; locus:2055552; AT2G45080.
DR eggNOG; KOG1674; Eukaryota.
DR HOGENOM; CLU_057371_0_1_1; -.
DR InParanoid; Q9SHD3; -.
DR OMA; DMMERLM; -.
DR OrthoDB; 1276824at2759; -.
DR PhylomeDB; Q9SHD3; -.
DR PRO; PR:Q9SHD3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SHD3; baseline and differential.
DR Genevisible; Q9SHD3; AT.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR012389; Cyclin_P/U.
DR InterPro; IPR013922; Cyclin_PHO80-like.
DR PANTHER; PTHR15615; PTHR15615; 1.
DR Pfam; PF08613; Cyclin; 1.
DR PIRSF; PIRSF027110; PREG; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..222
FT /note="Cyclin-U2-1"
FT /id="PRO_0000287069"
SQ SEQUENCE 222 AA; 25819 MW; 98DD6C7530C5DA84 CRC64;
MDSLAISPRK LRSDLYSYSY QDDSNTVPLV ISVLSSLIER TLARNERISR SYGGFGKTRV
FDCREIPDMT IQSYLERIFR YTKAGPSVYV VAYVYIDRFC QNNQGFRISL TNVHRLLITT
IMIASKYVED MNYKNSYFAK VGGLETEDLN NLELEFLFLM GFKLHVNVSV FESYCCHLER
EVSIGGGYQI EKALRCAEEI KSRQIVQDPK HHHHHQFSRI ML
