CCU41_ARATH
ID CCU41_ARATH Reviewed; 202 AA.
AC O80513;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Cyclin-U4-1;
DE Short=CycU4;1;
DE AltName: Full=Cyclin-P4.1;
DE Short=CycP4;1;
GN Name=CYCU4-1; OrderedLocusNames=At2g44740; ORFNames=F16B22.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY, AND INTERACTION WITH CDKA-1.
RX PubMed=15197472; DOI=10.1007/s00018-004-4057-4;
RA Torres Acosta J.A., de Almeida Engler J., Raes J., Magyar Z., de Groodt R.,
RA Inze D., de Veylder L.;
RT "Molecular characterization of Arabidopsis PHO80-like proteins, a novel
RT class of CDKA;1-interacting cyclins.";
RL Cell. Mol. Life Sci. 61:1485-1497(2004).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
CC -!- SUBUNIT: Interacts with CDKA-1. {ECO:0000269|PubMed:15197472}.
CC -!- INTERACTION:
CC O80513; P24100: CDKA-1; NbExp=2; IntAct=EBI-1773819, EBI-371713;
CC O80513; Q94ID6: ERF12; NbExp=3; IntAct=EBI-1773819, EBI-4446727;
CC O80513; Q84MB2: TIFY8; NbExp=5; IntAct=EBI-1773819, EBI-4426557;
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and flowers. Expressed in
CC the shoot apex, leaf primordia and young leaves.
CC {ECO:0000269|PubMed:15197472}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin U/P subfamily.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC003672; AAC27476.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10461.1; -; Genomic_DNA.
DR EMBL; BT021978; AAY17415.1; -; mRNA.
DR EMBL; BT023473; AAY57312.1; -; mRNA.
DR EMBL; AK229380; BAF01242.1; -; mRNA.
DR PIR; T01601; T01601.
DR RefSeq; NP_182002.1; NM_130038.4.
DR AlphaFoldDB; O80513; -.
DR SMR; O80513; -.
DR BioGRID; 4418; 3.
DR IntAct; O80513; 3.
DR STRING; 3702.AT2G44740.1; -.
DR PaxDb; O80513; -.
DR PRIDE; O80513; -.
DR EnsemblPlants; AT2G44740.1; AT2G44740.1; AT2G44740.
DR GeneID; 819082; -.
DR Gramene; AT2G44740.1; AT2G44740.1; AT2G44740.
DR KEGG; ath:AT2G44740; -.
DR Araport; AT2G44740; -.
DR TAIR; locus:2042421; AT2G44740.
DR eggNOG; KOG1674; Eukaryota.
DR HOGENOM; CLU_057371_1_1_1; -.
DR InParanoid; O80513; -.
DR OMA; YCAYLQK; -.
DR OrthoDB; 1153955at2759; -.
DR PhylomeDB; O80513; -.
DR PRO; PR:O80513; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80513; baseline and differential.
DR Genevisible; O80513; AT.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR012389; Cyclin_P/U.
DR InterPro; IPR013922; Cyclin_PHO80-like.
DR PANTHER; PTHR15615; PTHR15615; 1.
DR Pfam; PF08613; Cyclin; 1.
DR PIRSF; PIRSF027110; PREG; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..202
FT /note="Cyclin-U4-1"
FT /id="PRO_0000287072"
SQ SEQUENCE 202 AA; 23043 MW; 65C7AA5A09AA0ACB CRC64;
MAELENPSVM SKLIAFLSSL LERVAESNDL TRRVATQSQR VSVFHGLSRP TITIQSYLER
IFKYANCSPS CFVVAYVYLD RFTHRQPSLP INSFNVHRLL ITSVMVAAKF LDDLYYNNAY
YAKVGGISTK EMNFLELDFL FGLGFELNVT PNTFNAYFSY LQKEMTLLQP LSLVVVPSSR
SLITFNDDEA SHQKQQQQQL AV
