ID   CCU83_HHV6U             Reviewed;          97 AA.
AC   P52460;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   02-JUN-2021, entry version 70.
DE   RecName: Full=Putative CC-type chemokine U83;
DE   Flags: Precursor;
GN   Name=U83; Synonyms=EDRF3;
OS   Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B
OS   lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=10370;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7747482; DOI=10.1006/viro.1995.1228;
RA   Gompels U.A., Nicholas J., Lawrence G.L., Jones M., Thomson B.J.,
RA   Martin M.E.D., Efstathiou S., Craxton M.A., Macaulay H.A.;
RT   "The DNA sequence of human herpesvirus-6: structure, coding content, and
RT   genome evolution.";
RL   Virology 209:29-51(1995).
CC   -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC       Highly divergent. {ECO:0000305}.
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DR   EMBL; X83413; CAA58332.1; -; Genomic_DNA.
DR   RefSeq; NP_042976.1; NC_001664.2.
DR   PRIDE; P52460; -.
DR   DNASU; 1487963; -.
DR   GeneID; 1487963; -.
DR   KEGG; vg:1487963; -.
DR   Proteomes; UP000009295; Genome.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR   InterPro; IPR035347; Putative_chemo_U83.
DR   Pfam; PF17465; U83; 1.
PE   3: Inferred from homology;
KW   Cytokine; Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..97
FT                   /note="Putative CC-type chemokine U83"
FT                   /id="PRO_0000005246"
FT   DISULFID        32..62
FT                   /evidence="ECO:0000250"
FT   DISULFID        33..76
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   97 AA;  10410 MW;  414124E60E0E9EDD CRC64;
     MAIGFICSSP DAELFSEKSR MSSSVLLGCL LCCMDWSAAV PGKTEPFRKL FDAIMIKKLK
     SCSAAYPSDL DEGSMCDMAD ASPTSLELGL SKLDKES