ID   CCU83_HHV6Z             Reviewed;          97 AA.
AC   P52461;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   02-JUN-2021, entry version 68.
DE   RecName: Full=Putative CC-type chemokine U83;
DE   Flags: Precursor;
GN   Name=U83; Synonyms=CB11R;
OS   Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=36351;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8634027; DOI=10.1007/bf01718406;
RA   Lindquester G.J., Inoue N., Allen R.D., Castelli J.W., Stamey F.R.,
RA   Dambaugh T.R., O'Brian J.J., Danovich R.M., Frenkel N., Pellett P.E.;
RT   "Restriction endonuclease mapping and molecular cloning of the human
RT   herpesvirus 6 variant B strain Z29 genome.";
RL   Arch. Virol. 141:367-379(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10482553; DOI=10.1128/jvi.73.10.8040-8052.1999;
RA   Dominguez G., Dambaugh T.R., Stamey F.R., Dewhurst S., Inoue N.,
RA   Pellett P.E.;
RT   "Human herpesvirus 6B genome sequence: coding content and comparison with
RT   human herpesvirus 6A.";
RL   J. Virol. 73:8040-8052(1999).
CC   -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC       Highly divergent. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB06367.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF157706; AAB06367.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_050262.1; NC_000898.1.
DR   PRIDE; P52461; -.
DR   DNASU; 1497083; -.
DR   GeneID; 1497083; -.
DR   KEGG; vg:1497083; -.
DR   Proteomes; UP000006930; Genome.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0008009; F:chemokine activity; IDA:CACAO.
DR   InterPro; IPR035347; Putative_chemo_U83.
DR   Pfam; PF17465; U83; 1.
PE   3: Inferred from homology;
KW   Cytokine; Disulfide bond; Reference proteome; Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..97
FT                   /note="Putative CC-type chemokine U83"
FT                   /id="PRO_0000005247"
FT   DISULFID        32..62
FT                   /evidence="ECO:0000250"
FT   DISULFID        33..76
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   97 AA;  10330 MW;  E8A268ED5959D9B0 CRC64;
     MAIGFIGSSP DAELSSENSR ISSSVLLGCL LCCTDWSAVV PGKTETFRKP FVAIMIKKLK
     SCFAAYLSDL EQGSMCDMAN ASPTSLELGL SKLDKES