ID   CCZ1_DICDI              Reviewed;         445 AA.
AC   Q54IQ5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Vacuolar fusion protein CCZ1 homolog;
GN   ORFNames=DDB_G0288589;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the CCZ1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000117; EAL63154.1; -; Genomic_DNA.
DR   RefSeq; XP_636659.1; XM_631567.1.
DR   AlphaFoldDB; Q54IQ5; -.
DR   SMR; Q54IQ5; -.
DR   STRING; 44689.DDB0305148; -.
DR   PaxDb; Q54IQ5; -.
DR   EnsemblProtists; EAL63154; EAL63154; DDB_G0288589.
DR   GeneID; 8626705; -.
DR   KEGG; ddi:DDB_G0288589; -.
DR   dictyBase; DDB_G0288589; -.
DR   eggNOG; KOG2622; Eukaryota.
DR   HOGENOM; CLU_037828_2_0_1; -.
DR   InParanoid; Q54IQ5; -.
DR   OMA; FLRAQNF; -.
DR   PhylomeDB; Q54IQ5; -.
DR   Reactome; R-DDI-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q54IQ5; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0035658; C:Mon1-Ccz1 complex; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR013176; Ccz1.
DR   InterPro; IPR043987; CCZ1/INTU/HSP4_longin_1.
DR   InterPro; IPR043989; CCZ1/INTU/HSP4_longin_3.
DR   PANTHER; PTHR13056; PTHR13056; 2.
DR   Pfam; PF19031; Intu_longin_1; 1.
DR   Pfam; PF19033; Intu_longin_3; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..445
FT                   /note="Vacuolar fusion protein CCZ1 homolog"
FT                   /id="PRO_0000327406"
SQ   SEQUENCE   445 AA;  51636 MW;  F1FCE3386F29018F CRC64;
     MSVPIVETSL HYFVIYCSKL GQKEGTEHEK ILFFYPPTIN IGEQTNSVGI SEAYVLFTKQ
     FSPGQPCEFI HTKKSTLALL HPEEDIWMVL SVYNPTGITG KDNKREYIED EVDDIILMKT
     IQQIYQTWQT FNGSIMSLAS KTSYDNVRKR LESFVKPYIQ QIQFDQLDLF TSLDGIKFLP
     LNKNVYLTIF GYINSVDLHF QSTLSSFRFG LVLYKDNLIL SSLEQNETRI LYNYLINMVK
     VGPDINSSNS MIVKNNSNNI PIWQTKGVRT GFMIQKDSLP MVWLGGKPQA MIVYEQKDTF
     LLFLIDPSDL PQLPFEDLSA SLVQNFEFVN LTLEQHYAKK ANFDEQYKYI YFNQMNLAIR
     SPIKPKGPEL NKETMKLLNE IHADFEGGLS SEIIVKTQQD RWIVAKKIDF REFYIMFDNK
     NSSILEINEE VKNATTKFFK FLFTD