ID   CCZ1_XENLA              Reviewed;         471 AA.
AC   Q7T102;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Vacuolar fusion protein CCZ1 homolog;
GN   Name=ccz1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCZ1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC055965; AAH55965.1; -; mRNA.
DR   RefSeq; NP_001080322.1; NM_001086853.1.
DR   RefSeq; XP_018092724.1; XM_018237235.1.
DR   RefSeq; XP_018092725.1; XM_018237236.1.
DR   RefSeq; XP_018092726.1; XM_018237237.1.
DR   AlphaFoldDB; Q7T102; -.
DR   SMR; Q7T102; -.
DR   DNASU; 380014; -.
DR   GeneID; 380014; -.
DR   KEGG; xla:380014; -.
DR   CTD; 380014; -.
DR   OMA; WVIARLN; -.
DR   OrthoDB; 448107at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 380014; Expressed in gastrula and 19 other tissues.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0035658; C:Mon1-Ccz1 complex; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR013176; Ccz1.
DR   InterPro; IPR043987; CCZ1/INTU/HSP4_longin_1.
DR   InterPro; IPR043989; CCZ1/INTU/HSP4_longin_3.
DR   InterPro; IPR043988; CCZ1/INTU_longin_2.
DR   PANTHER; PTHR13056; PTHR13056; 1.
DR   Pfam; PF19031; Intu_longin_1; 1.
DR   Pfam; PF19032; Intu_longin_2; 1.
DR   Pfam; PF19033; Intu_longin_3; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..471
FT                   /note="Vacuolar fusion protein CCZ1 homolog"
FT                   /id="PRO_0000327403"
SQ   SEQUENCE   471 AA;  55122 MW;  5130790A57163EAB CRC64;
     MAFAGQDKRY APSLLSFFIY NPKFGPREGE EEKKILFYHP NEVEQNEKIR NVGLCEAIVQ
     FTRTFNPTKP AKSLHTQKNR QFFHEPEEGF WMVMVVKNPV AEKQKDGKTV LEYQEDELLD
     KVYSSVLQQC YRMYKLFNGT FGRAMEVGQV ELLKDRLEKF FHRYLQTLHL HSCDLLDVFG
     GISFFPLDKM TYLKVQSFIN RIEESLNIVK YTAFLYNDQL IWSGLEQEDM RILYKYLTTT
     LFPRYTEPEL AGRDSPIRPE MPGNLQHYGR FLTGPLNLND SEVKFRFPKI FVNTEDSYEE
     LHLIVYKAMS ASVCFMIDAS VQLTVDFCRK LDSLVGPQLT VLASDICEQY NSNRRISGSE
     KEPQFKFIYF NHMNLAEKST IHLRKTPNMS LTSVQPELMK ILGDINSDFT RVDEDEEIIV
     KAMSDYWVVG KKSDQRELYV ILNQKNSNLI EVNEEIKKLC ATHFSNIFFL D