ID   CCZ1_XENTR              Reviewed;         471 AA.
AC   Q28HU2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Vacuolar fusion protein CCZ1 homolog;
GN   Name=ccz1; ORFNames=TGas077n04.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Lysosome membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCZ1 family. {ECO:0000305}.
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DR   EMBL; CR760737; CAJ83427.1; -; mRNA.
DR   AlphaFoldDB; Q28HU2; -.
DR   SMR; Q28HU2; -.
DR   STRING; 8364.ENSXETP00000058579; -.
DR   PaxDb; Q28HU2; -.
DR   eggNOG; KOG2622; Eukaryota.
DR   InParanoid; Q28HU2; -.
DR   Proteomes; UP000008143; Genome assembly.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0035658; C:Mon1-Ccz1 complex; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   InterPro; IPR013176; Ccz1.
DR   InterPro; IPR043987; CCZ1/INTU/HSP4_longin_1.
DR   InterPro; IPR043989; CCZ1/INTU/HSP4_longin_3.
DR   InterPro; IPR043988; CCZ1/INTU_longin_2.
DR   PANTHER; PTHR13056; PTHR13056; 1.
DR   Pfam; PF19031; Intu_longin_1; 1.
DR   Pfam; PF19032; Intu_longin_2; 1.
DR   Pfam; PF19033; Intu_longin_3; 1.
PE   2: Evidence at transcript level;
KW   Lysosome; Membrane; Reference proteome.
FT   CHAIN           1..471
FT                   /note="Vacuolar fusion protein CCZ1 homolog"
FT                   /id="PRO_0000327404"
SQ   SEQUENCE   471 AA;  55218 MW;  36430B4FBBD75E37 CRC64;
     MAYAVQDKRF APSLLSFFIY NPKFGPREGE EEKKILFYHP NEVEKNEKIR NVGLCEAIVQ
     FTRTFNPTKP AKSLHTQKNR QFFHEPEEGF WMVMVVKNPL AEKQKEGKTV LEYQEDELLD
     KVYSSVLQQC YRMYKLFNGT FSRAMEVGQV ELLKDRLEKF FHRYLQTLHL HSCDLLDVFG
     GISFFPLDKM TYLKIQSFIN RIEESLNIVK YTVFLYNDQL IWSGLEQEDM RILYKYLTTT
     LFPRYTEPEL AGRDSPIRPE MPGNLQHYGR FLTGPLNLSD PEVKFRFPKI FVNTEDSYEE
     LYLIVYKAMS ASVCFMIDAS VQLTVDFCRK LDSLVGPQLT VLASDICEQF NINRRISGSE
     KEPQFKFIYF NHMNLAEKST IHLRKTPSMS LTSVQPELMK ILGDINGDFT RVDEDEEIIV
     KAMSDYWVVG KKSDQRELYV ILNQKNSNLI EVNEEIKKLC ATQFSNIFFL D