CD046_MOUSE
ID CD046_MOUSE Reviewed; 111 AA.
AC Q3UUX7; Q9D4P8;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Uncharacterized protein C4orf46 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis, and Thymus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Olfactory epithelium;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q504U0}.
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DR EMBL; AK016321; BAB30193.1; -; mRNA.
DR EMBL; AK137776; BAE23496.1; -; mRNA.
DR EMBL; BC052483; -; NOT_ANNOTATED_CDS; mRNA.
DR CCDS; CCDS50936.1; -.
DR RefSeq; NP_083758.1; NM_029482.1.
DR AlphaFoldDB; Q3UUX7; -.
DR SMR; Q3UUX7; -.
DR STRING; 10090.ENSMUSP00000029388; -.
DR iPTMnet; Q3UUX7; -.
DR PhosphoSitePlus; Q3UUX7; -.
DR EPD; Q3UUX7; -.
DR MaxQB; Q3UUX7; -.
DR PaxDb; Q3UUX7; -.
DR PeptideAtlas; Q3UUX7; -.
DR PRIDE; Q3UUX7; -.
DR Antibodypedia; 53666; 139 antibodies from 17 providers.
DR Ensembl; ENSMUST00000029388; ENSMUSP00000029388; ENSMUSG00000027811.
DR GeneID; 75939; -.
DR KEGG; mmu:75939; -.
DR UCSC; uc008pnu.2; mouse.
DR MGI; MGI:1923189; 4930579G24Rik.
DR VEuPathDB; HostDB:ENSMUSG00000027811; -.
DR eggNOG; ENOG502SUFC; Eukaryota.
DR GeneTree; ENSGT00390000003125; -.
DR HOGENOM; CLU_171943_0_0_1; -.
DR InParanoid; Q3UUX7; -.
DR OMA; FKCMENA; -.
DR OrthoDB; 1562931at2759; -.
DR TreeFam; TF338687; -.
DR BioGRID-ORCS; 75939; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q3UUX7; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q3UUX7; protein.
DR Bgee; ENSMUSG00000027811; Expressed in humerus cartilage element and 186 other tissues.
DR Genevisible; Q3UUX7; MM.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR031457; RCDG1.
DR PANTHER; PTHR31641; PTHR31641; 1.
DR Pfam; PF15725; RCDG1; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..111
FT /note="Uncharacterized protein C4orf46 homolog"
FT /id="PRO_0000335690"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 106
FT /note="S -> P (in Ref. 1; BAB30193)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 111 AA; 11861 MW; F366716AA15499B9 CRC64;
MADSEEFRAS SPPPPPPSSP SSGASSSSLS MPVSLGWRDP SRSPGPTVDP LEQVELQIGD
AAFSLTKLLE ATSAVSAQVE ELALKCTENA RFLKTWRDLL KEGYDSLKPD N