ID   CD123_ASHGO             Reviewed;         355 AA.
AC   Q75A37;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=CDC123; OrderedLocusNames=ADR082C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS52002.1; -; Genomic_DNA.
DR   RefSeq; NP_984178.1; NM_209531.1.
DR   AlphaFoldDB; Q75A37; -.
DR   SMR; Q75A37; -.
DR   STRING; 33169.AAS52002; -.
DR   EnsemblFungi; AAS52002; AAS52002; AGOS_ADR082C.
DR   GeneID; 4620327; -.
DR   KEGG; ago:AGOS_ADR082C; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   InParanoid; Q75A37; -.
DR   OMA; FTWHELL; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
DR   PIRSF; PIRSF007807; Cdc123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..355
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000227683"
SQ   SEQUENCE   355 AA;  40512 MW;  7557981299B1E4F2 CRC64;
     MSTEDAALTG IAVTAELKKK CAFSSWYEAF KGHTPRAEVI RPLPEEFVSY VDQRGIRLAR
     EEGSKYFYGQ ELEPTTDGEY SDWEGGDSAS ERSFVPLDPV ADFPEVHARV KQAIARFGAV
     APKLNRSAPK DAMWRLRNYS MKCNEANDVY LLLNGSSHVA CDVSDTLLDW LASTEDEPVM
     ELVLREWLDV NPALEFRVFV RGGEVLGACQ RDLNYYDYLK PLEEKLRTAI EDFVHDVMLQ
     RLPDDTFVAD VYIPRPFTKV WLIDVNPFAR ETDPLLFSWN ELCTLKPNAE GQPELRLVAE
     NYIGRFAENN IGRFAAKEHS EHQVPLDVVE AGLNPQSMQK LVETWRDLLK IQEEE