CD123_ASPCL
ID CD123_ASPCL Reviewed; 421 AA.
AC A1CMB9;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=Cell division cycle protein 123;
GN Name=cdc123; ORFNames=ACLA_096390;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR EMBL; DS027058; EAW08706.1; -; Genomic_DNA.
DR RefSeq; XP_001270132.1; XM_001270131.1.
DR AlphaFoldDB; A1CMB9; -.
DR SMR; A1CMB9; -.
DR STRING; 5057.CADACLAP00008958; -.
DR EnsemblFungi; EAW08706; EAW08706; ACLA_096390.
DR GeneID; 4702353; -.
DR KEGG; act:ACLA_096390; -.
DR VEuPathDB; FungiDB:ACLA_096390; -.
DR eggNOG; KOG2983; Eukaryota.
DR HOGENOM; CLU_034402_2_0_1; -.
DR OMA; RDLNHFD; -.
DR OrthoDB; 1539674at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR InterPro; IPR009772; CDC123.
DR PANTHER; PTHR15323; PTHR15323; 1.
DR Pfam; PF07065; D123; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT CHAIN 1..421
FT /note="Cell division cycle protein 123"
FT /id="PRO_0000350935"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..98
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..352
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 48182 MW; 4B776E83AF9BB05F CRC64;
MPHQESESQA QAESSNEQLE RLPFPPIPYS HILHCSYHHW QPRYRTITPK SRLIPLTDPF
VSYLRADGIV LPPENTSPQD EDDLDTFSDD GADEEPDPSV EWQDIHSQIK STISEFGGKV
TPKLNWSAPK DAVWMSATND LQCRTPNDIY LLLKSSDFVT HDLEHPFDDC VPDTTETTES
SDAQPEIPYH LVLRKYVNFN PALEFRCFVR NRVLLCMCQR DQNHFDFLFG LRDTLRSRIQ
AFFDEHLKDS FPDPNFVFDM YIPAPYQRVW LVDINPWAPR TDPLLFSWLE ILHMRDPIGI
QEADDDAPEQ FVRLSLNGDN LTILDVGGNE GSDSGSESEA EAEGDAEDDD DSPFLPEFRL
IKRDDPEAYA FTTPQYSAHK LPREVVDASL TGPGGMSEFL GKWQEILAKQ EQEDTESEDG
R
