ID   CD123_ASPOR             Reviewed;         413 AA.
AC   Q2U988;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=cdc123; ORFNames=AO090701000129;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; AP007164; BAE61877.1; -; Genomic_DNA.
DR   RefSeq; XP_001823010.1; XM_001822958.2.
DR   AlphaFoldDB; Q2U988; -.
DR   SMR; Q2U988; -.
DR   STRING; 510516.Q2U988; -.
DR   EnsemblFungi; BAE61877; BAE61877; AO090701000129.
DR   GeneID; 5995067; -.
DR   KEGG; aor:AO090701000129; -.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   OMA; RDLNHFD; -.
DR   Proteomes; UP000006564; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:EnsemblFungi.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:EnsemblFungi.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:1905143; P:eukaryotic translation initiation factor 2 complex assembly; IEA:EnsemblFungi.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IEA:EnsemblFungi.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..413
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000350938"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          71..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..98
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..342
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   413 AA;  46822 MW;  6370519300FA0DA0 CRC64;
     MPHSDTEVPA SAEASTDLPQ RLPFPPVTHS HILHCSYHDW QPRYRALTPK SRLIPLTVPF
     ISYLRADGIV LPPENATPTD DDNLDTYSDD EADEQPDPST EWEEIHTQIK TTISELGGII
     TPKLNWSAPK DATWMAATND MQCRTPNDIY LLLKSSDFIS HDLELPFDDC VPDMPDSTTT
     PDVPYHLVLR KYVNFNPSLE FRCFVRDRVL LCICQRDQNH FDFLFPLRET LRSRIQAFFD
     EKLKDTFPDP SFVFDVYIPP PHQRVWLIDI NPWAVRTDPL LFSWLEILNM KDPIGIQEED
     GAEEQFVRLS LNGNTVTGVV GAAEGSESSD TEDESADDVD EDSPFFPEFR LVKRDDPEAY
     AFTTPQYSAH KLPKEVVDAS ISGPGGMSEF LGKWQDILAK QAQESDTDSD GGQ