ID   CD123_BOVIN             Reviewed;         335 AA.
AC   Q2YDG3;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Cell division cycle protein 123 homolog;
GN   Name=CDC123;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for S phase entry of the cell cycle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; BC110235; AAI10236.1; -; mRNA.
DR   RefSeq; NP_001073743.1; NM_001080274.2.
DR   AlphaFoldDB; Q2YDG3; -.
DR   SMR; Q2YDG3; -.
DR   STRING; 9913.ENSBTAP00000025992; -.
DR   PaxDb; Q2YDG3; -.
DR   PRIDE; Q2YDG3; -.
DR   Ensembl; ENSBTAT00000025992; ENSBTAP00000025992; ENSBTAG00000019511.
DR   GeneID; 514926; -.
DR   KEGG; bta:514926; -.
DR   CTD; 8872; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019511; -.
DR   VGNC; VGNC:27058; CDC123.
DR   eggNOG; KOG2983; Eukaryota.
DR   GeneTree; ENSGT00390000003057; -.
DR   HOGENOM; CLU_034402_0_0_1; -.
DR   InParanoid; Q2YDG3; -.
DR   OMA; RDLNHFD; -.
DR   OrthoDB; 1539674at2759; -.
DR   TreeFam; TF323348; -.
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000019511; Expressed in tongue muscle and 105 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
DR   PIRSF; PIRSF007807; Cdc123; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..335
FT                   /note="Cell division cycle protein 123 homolog"
FT                   /id="PRO_0000228661"
FT   MOD_RES         60
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O75794"
SQ   SEQUENCE   335 AA;  38923 MW;  7AD08F1BC97A5464 CRC64;
     MKKEHVLHCQ FSAWYPLFRS LTIKSVILPL PQNVKDYLLD DGTLVVSGRE DPPAHSQPDS
     DDEAEEIQWS DDENTATLTA PEFPEFTTKV QEAINSLGGS VFPKLNWSAP RDAYWIAMNS
     SLKCKTLSDI FLLFKSSDFI TRDFTQPFIH CTDDSPDPCM EYELVLRKWC ELIPGAEFRC
     FVKENKLIGI SQRDYTQYYD HISKQKEEIC RCIQDFFKKH IQYKFLDEDF VFDIYRDSRG
     KVWLIDFNPF GEVTDSLLFT WDELLSGTNL KGDFSEEALE QDAPAFRCTN SEVTVQPSPY
     LSYRLPKDFV DLSTGEDAHK LIDFLKLKRN QQEDD