ID   CD123_CANGA             Reviewed;         355 AA.
AC   Q6FNU7;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=CDC123; OrderedLocusNames=CAGL0J08932g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG61048.1; -; Genomic_DNA.
DR   RefSeq; XP_448097.1; XM_448097.1.
DR   AlphaFoldDB; Q6FNU7; -.
DR   SMR; Q6FNU7; -.
DR   STRING; 5478.XP_448097.1; -.
DR   PRIDE; Q6FNU7; -.
DR   EnsemblFungi; CAG61048; CAG61048; CAGL0J08932g.
DR   GeneID; 2889472; -.
DR   KEGG; cgr:CAGL0J08932g; -.
DR   CGD; CAL0133660; CAGL0J08932g.
DR   VEuPathDB; FungiDB:CAGL0J08932g; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   InParanoid; Q6FNU7; -.
DR   OMA; RDLNHFD; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:EnsemblFungi.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:EnsemblFungi.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:1905143; P:eukaryotic translation initiation factor 2 complex assembly; IEA:EnsemblFungi.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IEA:EnsemblFungi.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
DR   PIRSF; PIRSF007807; Cdc123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..355
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000350942"
SQ   SEQUENCE   355 AA;  41529 MW;  3EFF81E734CE2B8C CRC64;
     MSEEYAVLSE LPVTCSQIDN CAFSFWYEKF KKHVPKSRVI KPLPEQFIQY LEQDGIKLPM
     SSTELSTYTD DVARTEDNEY SDWEGDEDTA TEYEPGIEPL NDFPELHNQI KEIIVELGPV
     TPKLNWSAPK DATWILPNNT TKCNEVNEIY LLLNASNYIV HDLNHAYDEC IDKKEGFSTP
     EYELVLRQWF AINPALEFRV FVKDGKVAAV SQRDLNYYDY LDKLTDTFKD LIDEFVEDEM
     VPQFPDKSFV TDLYIPRPFN RVFLIDINPF SRKTDPLLFT WNEIININAQ PDRDYELRLI
     TENNIGRFAS KEHSQNHVPK DVVDASLDPE RIRELSQKWS ELLLQQEKES SDEEK