ID   CD123_LODEL             Reviewed;         387 AA.
AC   A5E3J7;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=CDC123; ORFNames=LELG_04184;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; CH981529; EDK46005.1; -; Genomic_DNA.
DR   RefSeq; XP_001524214.1; XM_001524164.1.
DR   AlphaFoldDB; A5E3J7; -.
DR   SMR; A5E3J7; -.
DR   STRING; 379508.A5E3J7; -.
DR   PRIDE; A5E3J7; -.
DR   EnsemblFungi; EDK46005; EDK46005; LELG_04184.
DR   GeneID; 5231742; -.
DR   KEGG; lel:LELG_04184; -.
DR   VEuPathDB; FungiDB:LELG_04184; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   InParanoid; A5E3J7; -.
DR   OMA; FTWHELL; -.
DR   OrthoDB; 1539674at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..387
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000350945"
SQ   SEQUENCE   387 AA;  44343 MW;  EEEE9F01CC955DB1 CRC64;
     MTDYAKFEEI DLTVEEVLNC SFSKWAPLFP KNVFPYKIIA PLPDGFIDYV QSDGIKLPSA
     KTNKIVLEQN SDNEYSDWED VEDIENDTGE VEEMHSESQK NYEEKEVLEA SGHFPQLNQE
     ITQSIAELGG KVIPKLNWSS PKDASWLMPG NVIKCTEVDD VLLLLKSSDH VIDDLAYPFL
     EVSQLPEDET RKNGQDRIKV DYELVLKQWR DLNPALEFRV FVKEGKILGI SQRDLNHYDF
     LKELEPQLKE NIQLFVTDKV VNKLNASLPN LTKFIVDVYV PRPFDKIYII DINPFLRKSD
     SLLFTWNELL TADPDSDTVP FRLINETNVG AFAKKQYSES QVPLDVIGAA QDHEALIELA
     KEWEKLQSKE AEEEDEAVVV DGVIEEK