ID   CD123_MACFA             Reviewed;         336 AA.
AC   Q2PG37;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Cell division cycle protein 123 homolog;
GN   Name=CDC123; ORFNames=QccE-12339;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for S phase entry of the cell cycle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; AB220400; BAE72933.1; -; mRNA.
DR   RefSeq; NP_001271660.1; NM_001284731.1.
DR   AlphaFoldDB; Q2PG37; -.
DR   SMR; Q2PG37; -.
DR   STRING; 9541.XP_005564679.1; -.
DR   Ensembl; ENSMFAT00000026158; ENSMFAP00000007468; ENSMFAG00000036128.
DR   GeneID; 102117547; -.
DR   CTD; 8872; -.
DR   VEuPathDB; HostDB:ENSMFAG00000036128; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   GeneTree; ENSGT00390000003057; -.
DR   OMA; RDLNHFD; -.
DR   OrthoDB; 1539674at2759; -.
DR   Proteomes; UP000233100; Chromosome 9.
DR   Bgee; ENSMFAG00000036128; Expressed in skeletal muscle tissue and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
DR   PIRSF; PIRSF007807; Cdc123; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Cytoplasm; Phosphoprotein; Reference proteome.
FT   CHAIN           1..336
FT                   /note="Cell division cycle protein 123 homolog"
FT                   /id="PRO_0000228663"
FT   MOD_RES         60
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O75794"
SQ   SEQUENCE   336 AA;  39048 MW;  180191C683FE90D7 CRC64;
     MKKEHVLHCQ FSAWYPLFRG VTIKSVILPL PQNVKDYLLD DGTLVVSGRD DPPTHSQPDS
     DDEAEEIQWS DDENTATLTA PEFPEFATQV QEAINSLGGS VFPKLNWSAP RDAYWIAMNS
     SLKCKTLSDI FLLFKSSDFI TRDFTQPFIH CTDDSPDPCI EYELVLRKWC ELIPGAEFRC
     FVKENKLIGI SQRDYTQYYD HISKQKEEIC RCIQDFFKKH IQYKFLDEDF VFDIYRDSRG
     KVWLIDFNPF GEVTDSLLFT WEELISENNL NGDFSEVDAQ EQDSPAFRCT NSEVTVQPSP
     YLSYRLPKDF VDLSTGEDAH KLIDFLKLKR NQQEDD