ID   CD123_NEMVE             Reviewed;         329 AA.
AC   A7RFT2;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Cell division cycle protein 123 homolog;
GN   Name=cdc123; ORFNames=v1g233898;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Required for S phase entry of the cell cycle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; DS469508; EDO49775.1; -; Genomic_DNA.
DR   RefSeq; XP_001641838.1; XM_001641788.1.
DR   AlphaFoldDB; A7RFT2; -.
DR   SMR; A7RFT2; -.
DR   STRING; 45351.EDO49775; -.
DR   EnsemblMetazoa; EDO49775; EDO49775; NEMVEDRAFT_v1g233898.
DR   GeneID; 5521954; -.
DR   KEGG; nve:5521954; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_0_0_1; -.
DR   InParanoid; A7RFT2; -.
DR   OMA; RDLNHFD; -.
DR   OrthoDB; 1539674at2759; -.
DR   PhylomeDB; A7RFT2; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..329
FT                   /note="Cell division cycle protein 123 homolog"
FT                   /id="PRO_0000331561"
FT   REGION          46..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..76
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   329 AA;  37645 MW;  92688E0BBB34F397 CRC64;
     MKQQHVENCN FSSWYPRFKN VTIRSKIIPL SKEFVDYLKT DGVVLPGKPS SLPRHEDDES
     DSEEWQNLEE DPEQATVEAP EFNDIDTKIK EAIQELGGEV FPKLNWSAPR DASWISHDNT
     LRCKSPGDIY LLLKSSDTID RVLCDAFIHC EDNSTQTHDS FELILRKWQN IYPAMEFRCF
     VRNNELVAIS QRDISNYYHF LAENEDEICA DILNFYESKI AEKFPDTSYV FDVYKYADQK
     CTLIDFSPYG VPTNPLLFTW SELDTEVVPD LLFKVVPSAI GVQPGPFACS RLPQDMVDLT
     SGADVNKLVD FLNVGNLIRR PGEASDDDS