ID   CD123_NEOFI             Reviewed;         418 AA.
AC   A1DLP3;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=cdc123; ORFNames=NFIA_050590;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS027698; EAW15714.1; -; Genomic_DNA.
DR   RefSeq; XP_001257611.1; XM_001257610.1.
DR   AlphaFoldDB; A1DLP3; -.
DR   SMR; A1DLP3; -.
DR   STRING; 36630.CADNFIAP00004810; -.
DR   EnsemblFungi; EAW15714; EAW15714; NFIA_050590.
DR   GeneID; 4584126; -.
DR   KEGG; nfi:NFIA_050590; -.
DR   VEuPathDB; FungiDB:NFIA_050590; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   OMA; RDLNHFD; -.
DR   OrthoDB; 1539674at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:EnsemblFungi.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:EnsemblFungi.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:1905143; P:eukaryotic translation initiation factor 2 complex assembly; IEA:EnsemblFungi.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IEA:EnsemblFungi.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..418
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000350946"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          71..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   418 AA;  47584 MW;  CCDDBF2BE9E1F627 CRC64;
     MPLLDPDTRS PAESSAAQPQ RLPFPPVTYS HILHCSYHHW QPRYRTLTPK SRAIPLTPSF
     VSYLRADGIV LPPETTRPQG DDDLDTFSDD GADEESDPSV EWQEIHSQIK STISEFGGKV
     TPKLNWSAPK DAVWMSATND LQCRTPNDIY LLLKSSDFIT HDLEHPFDGC VPDTDDSSEA
     PATQPDIPYH LVLRKYVNFN PSLEFRCFVR NRVLLCMCQR DQNHFDFLFS LRDTLRSRIQ
     AFFDEKLKDT FPDPNFVFDV YIPEPHQRVW LIDINPWADR TDPLLFSWLE ILQMKDPIGI
     KEEDADGPEE SFVRLSLNGA NPTVVEVNGD EDCESEEEDV GSADDGDDLP FLPEFRLVKR
     DDPEAYSFST PQYSAHKLPR EVVDASLSGP GGMSEFLGKW QDILAKQTQE DTDSDDGR