ID   CD123_VANPO             Reviewed;         369 AA.
AC   A7TPB3;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Cell division cycle protein 123;
GN   Name=CDC123; ORFNames=Kpol_1019p20;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Regulates the cell cycle in a nutrient dependent manner.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC123 family. {ECO:0000305}.
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DR   EMBL; DS480440; EDO15900.1; -; Genomic_DNA.
DR   RefSeq; XP_001643758.1; XM_001643708.1.
DR   AlphaFoldDB; A7TPB3; -.
DR   SMR; A7TPB3; -.
DR   STRING; 436907.A7TPB3; -.
DR   EnsemblFungi; EDO15900; EDO15900; Kpol_1019p20.
DR   GeneID; 5544007; -.
DR   KEGG; vpo:Kpol_1019p20; -.
DR   eggNOG; KOG2983; Eukaryota.
DR   HOGENOM; CLU_034402_2_0_1; -.
DR   InParanoid; A7TPB3; -.
DR   OMA; RDLNHFD; -.
DR   OrthoDB; 1539674at2759; -.
DR   PhylomeDB; A7TPB3; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR009772; CDC123.
DR   PANTHER; PTHR15323; PTHR15323; 1.
DR   Pfam; PF07065; D123; 1.
DR   PIRSF; PIRSF007807; Cdc123; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome.
FT   CHAIN           1..369
FT                   /note="Cell division cycle protein 123"
FT                   /id="PRO_0000350950"
SQ   SEQUENCE   369 AA;  43495 MW;  91C8B77856C331F9 CRC64;
     MNTDYTPLVN VPIKREDIET CRFSNWYPLF KKHCPTAEII GPLPAEFIEY LEQDGIKIPN
     ENRSFYSEDL TINDDNEYSD WDNEDDDEEE DKVIQQEVKK EIDPLADFPE LHRQIKDVIT
     KYGAVAPKMN WSAPKDATWI LPNNTMKCNE INEVYLLLNA SNYIAHDLQH AFDECEDIED
     QKKSSDFELV LRKWFDINPA LEFRIFIKDN EILGISQRDL NYYDYLEPLV DKFRDLIEDF
     IDDEILDRFP LKSFVIDLYI PRPFNKVFLI DINPFARMTD PLMFSWSELL TKNEPVTPIG
     QEEDYEFRLI KENNVGRFAC KEHSENQVPT DIVEASLNPE AIRELTQKWK ELLSKQSMEE
     DSSSDSNEE