ID   CD15L_HUMAN             Reviewed;         281 AA.
AC   A8MXV6;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=CMT1A duplicated region transcript 15 protein-like protein;
GN   Name=CDRT15L2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-189.
RA   Hillier L., Clark N., Dubuque T., Elliston K., Hawkins M., Holman M.,
RA   Hultman M., Kucaba T., Le M., Lennon G., Marra M., Parsons J., Rifkin L.,
RA   Rohlfing T., Soares M., Tan F., Trevaskis E., Waterston R., Williamson A.,
RA   Wohldmann P., Wilson R.;
RT   "The WashU-Merck EST project.";
RL   Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AC087499; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AA446206; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS54096.1; -.
DR   RefSeq; NP_001177719.1; NM_001190790.1.
DR   AlphaFoldDB; A8MXV6; -.
DR   BioGRID; 129146; 1.
DR   IntAct; A8MXV6; 1.
DR   STRING; 9606.ENSP00000382000; -.
DR   GlyGen; A8MXV6; 1 site, 1 O-linked glycan (1 site).
DR   iPTMnet; A8MXV6; -.
DR   PhosphoSitePlus; A8MXV6; -.
DR   BioMuta; CDRT15L2; -.
DR   jPOST; A8MXV6; -.
DR   MassIVE; A8MXV6; -.
DR   PaxDb; A8MXV6; -.
DR   PeptideAtlas; A8MXV6; -.
DR   PRIDE; A8MXV6; -.
DR   Antibodypedia; 58329; 109 antibodies from 10 providers.
DR   DNASU; 256223; -.
DR   Ensembl; ENST00000399044.1; ENSP00000382000.1; ENSG00000214819.2.
DR   GeneID; 256223; -.
DR   KEGG; hsa:256223; -.
DR   MANE-Select; ENST00000399044.1; ENSP00000382000.1; NM_001190790.2; NP_001177719.1.
DR   UCSC; uc021tsn.1; human.
DR   CTD; 256223; -.
DR   GeneCards; CDRT15L2; -.
DR   HGNC; HGNC:34075; CDRT15L2.
DR   HPA; ENSG00000214819; Tissue enriched (testis).
DR   neXtProt; NX_A8MXV6; -.
DR   VEuPathDB; HostDB:ENSG00000214819; -.
DR   eggNOG; ENOG502TF2R; Eukaryota.
DR   GeneTree; ENSGT00390000011755; -.
DR   HOGENOM; CLU_087008_0_0_1; -.
DR   InParanoid; A8MXV6; -.
DR   OMA; WMSVCSW; -.
DR   OrthoDB; 1363162at2759; -.
DR   PhylomeDB; A8MXV6; -.
DR   TreeFam; TF342212; -.
DR   PathwayCommons; A8MXV6; -.
DR   BioGRID-ORCS; 256223; 14 hits in 1027 CRISPR screens.
DR   GenomeRNAi; 256223; -.
DR   Pharos; A8MXV6; Tdark.
DR   PRO; PR:A8MXV6; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; A8MXV6; protein.
DR   Bgee; ENSG00000214819; Expressed in sperm and 40 other tissues.
DR   ExpressionAtlas; A8MXV6; baseline and differential.
DR   Genevisible; A8MXV6; HS.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..281
FT                   /note="CMT1A duplicated region transcript 15 protein-like
FT                   protein"
FT                   /id="PRO_0000349377"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          106..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   281 AA;  30100 MW;  A0FBE3DD9B17D4FC CRC64;
     MFSCCFPTSR GCCFRNGGSE SLFRQCRRRL IPHPRRLWPF VRRRTQVPQD SPGQALAGQA
     TPEIPSGLPL HIVLVQEEIR EPMEAQTHAP GPYADIAALA APAVEPKPAW EEPPPERALE
     VEGAPAKDQP SQELPEIMAP TVATGLNAGA ENVAGERSGR EGVTSTAPAS RSHAAPSPGH
     GGKHGGGDQG IQTGLLYLAG ERLLSFAGTT ALLLQGLFIV LILVGYISVK VMLKSIKTRL
     GRRVPAAPPA LRRNLLLQAW KCVCNWASRL FAPNVLPRTG S