ID   CD37L_DANRE             Reviewed;         313 AA.
AC   A7YY97;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Hsp90 co-chaperone Cdc37-like 1;
GN   Name=cdc37l1; ORFNames=zgc:171475;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Co-chaperone that binds to numerous proteins and promotes
CC       their interaction with Hsp70 and Hsp90. {ECO:0000250}.
CC   -!- SUBUNIT: Forms complexes with Hsp70 and Hsp90. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC37 family. {ECO:0000305}.
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DR   EMBL; BC152570; AAI52571.1; -; mRNA.
DR   RefSeq; NP_001103296.2; NM_001109826.2.
DR   AlphaFoldDB; A7YY97; -.
DR   SMR; A7YY97; -.
DR   STRING; 7955.ENSDARP00000110971; -.
DR   PaxDb; A7YY97; -.
DR   PeptideAtlas; A7YY97; -.
DR   GeneID; 569357; -.
DR   KEGG; dre:569357; -.
DR   CTD; 55664; -.
DR   ZFIN; ZDB-GENE-030131-8865; cdc37l1.
DR   eggNOG; KOG2260; Eukaryota.
DR   InParanoid; A7YY97; -.
DR   OrthoDB; 786744at2759; -.
DR   PhylomeDB; A7YY97; -.
DR   Reactome; R-DRE-114608; Platelet degranulation.
DR   PRO; PR:A7YY97; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0051087; F:chaperone binding; IBA:GO_Central.
DR   GO; GO:0031072; F:heat shock protein binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR   Gene3D; 1.20.58.610; -; 1.
DR   InterPro; IPR004918; Cdc37.
DR   InterPro; IPR013873; Cdc37_C.
DR   InterPro; IPR013874; Cdc37_Hsp90-bd.
DR   InterPro; IPR038189; Cdc37_Hsp90-bd_sf.
DR   PANTHER; PTHR12800; PTHR12800; 1.
DR   Pfam; PF08564; CDC37_C; 1.
DR   Pfam; PF08565; CDC37_M; 1.
DR   SMART; SM01069; CDC37_C; 1.
DR   SMART; SM01070; CDC37_M; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Cytoplasm; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Hsp90 co-chaperone Cdc37-like 1"
FT                   /id="PRO_0000318525"
SQ   SEQUENCE   313 AA;  36371 MW;  E7D1FABEABB92C4B CRC64;
     MASLCQRQQH CVKASIASEW QLAEAQDQLC GLELHSSESV EQERARALAS STELSHTEHQ
     WRLKERMLGT LCPEANRDVF DKSIINITQS WPNESDPDKS LNFVQRNEEL LKHFGMLGRW
     DDSQRFLAEY HHLICEETAN YLILWCFRLQ AEKKEALMEQ VAHQAVVMQF ILEMARNTQQ
     DPRGCFRHFF QKAKAGQEGY LDVFHTELQA FKDRVKEYTM KSTGETPKDT VHQNTPPACC
     LDPKEVFESL PQELKTCIQM QDMQILQNVL SSMNPQVAEY HVKRCLEAGL WTNIPRTSKD
     ESSEVDEWKM MET