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CDC4_CANAX
ID   CDC4_CANAX              Reviewed;         684 AA.
AC   P53699;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Cell division control protein 4;
GN   Name=CDC4;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SGY126;
RA   Shieh J.C., White A.M., Rosamond J.;
RL   Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: This protein is essential for initiation of DNA replication
CC       and separation of the spindle pole bodies to form the poles of the
CC       mitotic spindle. It also plays a role in bud development, fusion of
CC       zygotic nuclei after conjugation and various aspects of sporulation.
CC       Required for HTA1-HTB1 locus transcription activation (By similarity).
CC       {ECO:0000250}.
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DR   EMBL; X96763; CAA65538.1; -; Genomic_DNA.
DR   AlphaFoldDB; P53699; -.
DR   SMR; P53699; -.
DR   VEuPathDB; FungiDB:CAWG_01518; -.
DR   VEuPathDB; FungiDB:CR_01680C_A; -.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR031740; Cdc4_D.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF16856; CDC4_D; 1.
DR   Pfam; PF12937; F-box-like; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00256; FBOX; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Mitosis; Repeat; Sporulation; WD repeat.
FT   CHAIN           1..684
FT                   /note="Cell division control protein 4"
FT                   /id="PRO_0000050898"
FT   DOMAIN          212..258
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          322..351
FT                   /note="WD 1"
FT   REPEAT          363..391
FT                   /note="WD 2"
FT   REPEAT          403..431
FT                   /note="WD 3"
FT   REPEAT          442..468
FT                   /note="WD 4"
FT   REPEAT          478..506
FT                   /note="WD 5"
FT   REPEAT          519..549
FT                   /note="WD 6"
FT   REPEAT          561..589
FT                   /note="WD 7"
FT   REGION          1..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..108
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..146
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   684 AA;  76091 MW;  3DD65DB31293B107 CRC64;
     MPSCDDTASS DTDCQSQVSS TAHLHSYRSN GLVEPPSKRR LTTTNETSLS SAGATTFQIE
     SPGSISAITT NNSTTSAGDS NNSNSFSDQH SRHPRTPNAM NSPTHTPISD IEEDPIQQLP
     LPSPSASPIQ SDTENEHVTT PDSLQGKANL DSIENVMSNE PTTQSELVDL VTKLSGFLSE
     ANQNHLVFKL LQKTTRPTLS TFNNLINNSL KRDILSNVPF EVTMKILSYL DYKTLLSVAQ
     VCKKWFDIIN NPDTWIKLLK RDKLITDDAV IKYELQYPDQ LLREWSTLPE INSAQVLYKK
     RKIIVNRWMD PKFKPHRISV SGHGNKVVTC LQHDDEKVVT GVDDKCISIY STQTGQLMKV
     LEGHEGGVWA LKYTGNTLVT GSTDRTVRVW NMKTGQCTHI FRGHTSTIRC LDIIHPAVIG
     KNQDGEDIVF PEYPLLITGS RDHNIHVWKL PVVDDSQDYI ETFEGEFDNP YLIAVLSGHT
     QSVRSISGYG NIIISGSYDS TVRVWDLLDD GHCTHVLQGH LDRVYSTAID FHSKTCFSGS
     MDSNINVWNF ETGELKKVLV GHASLVGLLD LVDDVLVSAA ADATLRIWDA KTGELRSKLK
     GHGAAITCFE HDGLRVVSGS EKMLKLWNVE KGTFARDLLS DVTGGIWQVR FDYKRCVAAV
     QRIINEDEGE TFIEILDFSQ PLLQ
 
 
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