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CDC61_METMA
ID   CDC61_METMA             Reviewed;         414 AA.
AC   Q8PXA8;
DT   06-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=ORC1-type DNA replication protein 1 {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6-1; OrderedLocusNames=MM_1314;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; AE008384; AAM31010.1; -; Genomic_DNA.
DR   RefSeq; WP_011033260.1; NC_003901.1.
DR   AlphaFoldDB; Q8PXA8; -.
DR   SMR; Q8PXA8; -.
DR   STRING; 192952.MM_1314; -.
DR   PRIDE; Q8PXA8; -.
DR   EnsemblBacteria; AAM31010; AAM31010; MM_1314.
DR   GeneID; 44089072; -.
DR   GeneID; 66137253; -.
DR   KEGG; mma:MM_1314; -.
DR   PATRIC; fig|192952.21.peg.1526; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_1_2; -.
DR   OMA; DMLGIIN; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..414
FT                   /note="ORC1-type DNA replication protein 1"
FT                   /id="PRO_0000151004"
FT   BINDING         70..74
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         213
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         225
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   414 AA;  47151 MW;  D49C36D7BB1CDC50 CRC64;
     MIKAQSLDGL FEKLLDGKSI FKNKEVLRPS YTPDLLLHRN DQINSLATIL VSALRGETPS
     NVLIYGKTGT GKTAVTRYVG KELERVSEDK SIFCSVVYIN CEVIDTQYRL LANLARHFEE
     EVPMTGWPTD QVFMKFKEAI DSREQVIIII LDEIDKLIKK GDDVLYNLSR INTDLRKAKV
     SMIGVSNDLK FTEFLDPRVK SSLGEEELIF PPYDAEQISD ILKQRAKMAY NDGVLGEMVI
     PLCAAFAAQE HGDARRALDL LRVSGEIAER ENQPQVLEEH VRRAQEKIEI DRVVEVVRTL
     PTQSKLVLYS IILLRNRGRE GKNVTTGEMY NVYRQLCHHI DVDILTQRRV TDLMSELDML
     GIVNAVVVSK GRYGRTKEIS LSVPVENTRK VLLEDYRLKP LVDFKASVFN KMFS
 
 
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