ID   CDC62_SULAC             Reviewed;         415 AA.
AC   Q4JAB4;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=ORC1-type DNA replication protein 2 {ECO:0000255|HAMAP-Rule:MF_01407};
GN   Name=cdc6-2; OrderedLocusNames=Saci_0903;
OS   Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
OS   15157 / NCIMB 11770).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=330779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770;
RX   PubMed=15995215; DOI=10.1128/jb.187.14.4992-4999.2005;
RA   Chen L., Bruegger K., Skovgaard M., Redder P., She Q., Torarinsson E.,
RA   Greve B., Awayez M., Zibat A., Klenk H.-P., Garrett R.A.;
RT   "The genome of Sulfolobus acidocaldarius, a model organism of the
RT   Crenarchaeota.";
RL   J. Bacteriol. 187:4992-4999(2005).
CC   -!- FUNCTION: Involved in regulation of DNA replication.
CC       {ECO:0000255|HAMAP-Rule:MF_01407}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01407}.
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DR   EMBL; CP000077; AAY80266.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4JAB4; -.
DR   SMR; Q4JAB4; -.
DR   STRING; 330779.Saci_0903; -.
DR   EnsemblBacteria; AAY80266; AAY80266; Saci_0903.
DR   KEGG; sai:Saci_0903; -.
DR   PATRIC; fig|330779.12.peg.863; -.
DR   eggNOG; arCOG00467; Archaea.
DR   HOGENOM; CLU_025112_3_2_2; -.
DR   OMA; YLFYENE; -.
DR   Proteomes; UP000001018; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd08768; Cdc6_C; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR015163; Cdc6_C.
DR   InterPro; IPR014277; Orc1/Cdc6_arc.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09079; Cdc6_C; 1.
DR   SMART; SM01074; Cdc6_C; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02928; TIGR02928; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..415
FT                   /note="ORC1-type DNA replication protein 2"
FT                   /id="PRO_0000151016"
FT   BINDING         69..73
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         215
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT   BINDING         227
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ   SEQUENCE   415 AA;  47924 MW;  741F2446AA9A5A28 CRC64;
     MDDIKNLIED LLGGDTVFNN TKILNPEYIP SNLPHRENQI KEMTVSFRDL ILNPGSSSIR
     LVIIGRTGTG KSVTTKKFGL KLREIAHERN LRLEYVHVNC HRQRTLYLIL QEISQGLRLQ
     LPNRGLSSQE TFRIIYDYLE KRNIHLVITL DEFDYFVSTA PLEDIYFLVR VYDELNVTTK
     RLHYIFIVRE ITSLSGLDKS IKDHIIKNII DFPPYKSTEL YDILADRVYN EKAFKENSVS
     EDVLRFIAEV HGFDKGGSGN ARISIETLEL AGKIADSENS PIVTLEHAKK ANSKINPELS
     ALIDSIKELD LHQLIFLKAL VLLHDQEGID FFPIGKIEQR YVELSKNFGE EPRRHTQIFE
     YVRRMKLMGL INTRQSGRGM RGRTTLVSLP IPISMEFKDL INTEIRKRLE QSRIS