ID   CDC69_HALSA             Reviewed;         354 AA.
AC   O51974;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=ORC1-type DNA replication protein 9;
GN   Name=orc9-1;
GN   and
GN   Name=orc9-2; OrderedLocusNames=VNG_6091G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OG   Plasmid pNRC100, and Plasmid pNRC200.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC100;
RX   PubMed=9847077; DOI=10.1101/gr.8.11.1131;
RA   Ng W.V., Ciufo S.A., Smith T.M., Bumgarner R.E., Baskin D., Faust J.,
RA   Hall B., Loretz C., Seto J., Slagel J., Hood L., DasSarma S.;
RT   "Snapshot of a large dynamic replicon in a halophilic archaeon: megaplasmid
RT   or minichromosome?";
RL   Genome Res. 8:1131-1141(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC100, and pNRC200;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
RN   [3]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=17559652; DOI=10.1186/1471-2156-8-31;
RA   Berquist B.R., DasSarma P., DasSarma S.;
RT   "Essential and non-essential DNA replication genes in the model halophilic
RT   Archaeon, Halobacterium sp. NRC-1.";
RL   BMC Genet. 8:31-31(2007).
RN   [4]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=19502403; DOI=10.1128/jb.00210-09;
RA   Coker J.A., DasSarma P., Capes M., Wallace T., McGarrity K., Gessler R.,
RA   Liu J., Xiang H., Tatusov R., Berquist B.R., DasSarma S.;
RT   "Multiple replication origins of Halobacterium sp. strain NRC-1: properties
RT   of the conserved orc7-dependent oriC1.";
RL   J. Bacteriol. 191:5253-5261(2009).
CC   -!- FUNCTION: Involved in regulation of DNA replication. {ECO:0000250}.
CC   -!- DISRUPTION PHENOTYPE: Not essential for normal growth in a single
CC       deletion. Required together with orc2 and orc10 in a minimal orc
CC       strain. {ECO:0000269|PubMed:17559652, ECO:0000269|PubMed:19502403}.
CC   -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000305}.
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DR   EMBL; AF016485; AAC82854.1; -; Genomic_DNA.
DR   EMBL; AE004438; AAG20777.1; -; Genomic_DNA.
DR   PIR; T08287; T08287.
DR   AlphaFoldDB; O51974; -.
DR   SMR; O51974; -.
DR   EnsemblBacteria; AAC82854; AAC82854; AAC82854.
DR   EnsemblBacteria; AAG20777; AAG20777; VNG_6091G.
DR   KEGG; hal:AAC82854.1; -.
DR   KEGG; hal:VNG_6091G; -.
DR   PATRIC; fig|64091.14.peg.2145; -.
DR   HOGENOM; CLU_025112_0_0_2; -.
DR   InParanoid; O51974; -.
DR   OMA; SEIHERY; -.
DR   Proteomes; UP000000554; Plasmid pNRC100.
DR   Proteomes; UP000000554; Plasmid pNRC200.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF13401; AAA_22; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..354
FT                   /note="ORC1-type DNA replication protein 9"
FT                   /id="PRO_0000428866"
FT   BINDING         63..67
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         195
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
FT   BINDING         207
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   354 AA;  40462 MW;  D371BE0414C5E5E2 CRC64;
     MTCRRITFVP NFMIRDARVL RAGFVPREVE HRDAEVNHLS SVLEPITNGE PADTAIVTGP
     SGTGKTCISQ FVTERLREEV LNVEATYVNC WRNYTRFRTL YQILDDFGET IDIHRQSTPH
     DELIDRLQQY DGPRTVIILD EVDQLEDPGI IYDLHSLPHF AVICIANKEE DLFSRVDDRL
     VSRLRSSEHV RMDKYHDEQL HDILAARVKG GLDQDVITTN QLDRIADAAA GDARLAIGIL
     RTAASKADRE SRERITDDIL LNAAEDARAQ IKQKNLDSLI PHQRLVYDVV REHGPLGPSE
     IYDHYKRKVD DPRTKRTIRT YLSKMTQYNV LEAEGTSRDR EYSLVDSTAP SVTQ