CDC6B_ARATH
ID CDC6B_ARATH Reviewed; 505 AA.
AC Q8W032; Q9LML8;
DT 29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 139.
DE RecName: Full=Cell division control protein 6 homolog B {ECO:0000305};
DE Short=AtCDC6b {ECO:0000303|PubMed:11752380};
GN Name=CDC6B {ECO:0000303|PubMed:11752380};
GN OrderedLocusNames=At1g07270 {ECO:0000312|Araport:AT1G07270};
GN ORFNames=F10K1.2 {ECO:0000312|EMBL:AAF82194.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11752380; DOI=10.2307/3871527;
RA Castellano M.M., del Pozo J.C., Ramirez-Parra E., Brown S., Gutierrez C.;
RT "Expression and stability of Arabidopsis CDC6 are associated with
RT endoreplication.";
RL Plant Cell 13:2671-2686(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Stevens R.G., Ruelland E., Glab N., Perennes C., Bergounioux C.;
RT "Two cdc6 genes from Arabidopsis thaliana.";
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May be involved in the initiation of DNA replication.
CC {ECO:0000250|UniProtKB:O82387}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O82387}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF82194.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AJ310357; CAC83650.1; -; mRNA.
DR EMBL; AJ429229; CAD22139.1; -; mRNA.
DR EMBL; AC067971; AAF82194.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28099.1; -; Genomic_DNA.
DR PIR; A86208; A86208.
DR RefSeq; NP_172207.2; NM_100601.3.
DR AlphaFoldDB; Q8W032; -.
DR SMR; Q8W032; -.
DR STRING; 3702.AT1G07270.1; -.
DR PaxDb; Q8W032; -.
DR PRIDE; Q8W032; -.
DR ProMEX; Q8W032; -.
DR ProteomicsDB; 224449; -.
DR EnsemblPlants; AT1G07270.1; AT1G07270.1; AT1G07270.
DR GeneID; 837238; -.
DR Gramene; AT1G07270.1; AT1G07270.1; AT1G07270.
DR KEGG; ath:AT1G07270; -.
DR Araport; AT1G07270; -.
DR TAIR; locus:2007332; AT1G07270.
DR eggNOG; KOG2227; Eukaryota.
DR HOGENOM; CLU_012774_4_2_1; -.
DR InParanoid; Q8W032; -.
DR OMA; VCREDEH; -.
DR OrthoDB; 935804at2759; -.
DR PhylomeDB; Q8W032; -.
DR PRO; PR:Q8W032; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8W032; baseline and differential.
DR Genevisible; Q8W032; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003688; F:DNA replication origin binding; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR GO; GO:0033314; P:mitotic DNA replication checkpoint signaling; IBA:GO_Central.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041083; AAA_lid_10.
DR InterPro; IPR016314; Cdc6/18.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF17872; AAA_lid_10; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR PIRSF; PIRSF001767; Cdc6; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..505
FT /note="Cell division control protein 6 homolog B"
FT /id="PRO_0000432984"
FT REGION 37..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 55726 MW; 844816A665E7C934 CRC64;
MPTNAGTSLS SYKHIVAIGT TVKSESLESA AYEIPRKRKM RSDSAAVSGN SVSTPKKLKS
HLPSSVPNPG MSEKEVVEDS NEILRYPVNL AVSDCLGTKS KWSPRDEEQM RAVKEALHVS
KAPSTILCRE DEQIRIFEFV KGCIDQQKAG SLYICGCPGT GKSLSMEKVV QQVGDWSTQA
GLPPVDTLSV NCTSLSKTTD IFSKILGEIK PGKNANTNSS PLQHLQNLFS QKQESSSSRM
MLIIADEMDY LITKDRGVLY DLFMLTTLPF SRCILIGVAN AIDLADRFLP KLKSLNCKPM
VITFRAYSKD QILRILQERL RVLSYVAFQP KALELCARKV AAASGDMRKA LCVCRSALEI
LEIETRGSTG PESQGPTPDD SVVRMDHMAA ALSKTFKSPV VETIQSLPQH QQIIICAAAK
AFRGSKKDAT VGELNKLYLE ICKSWMISPA GITEFTNMCT VLNDQGILKV GQARRDKLKR
VSLRVDESDI TFALQEIRFF RNCLL
